New England Patriots vs Buffalo Bills Prediction & Picks - NFL

Prediction published on 1/5/25, 9:27 AM  by Bill Christy | Modified on 1/16/26 at 5:06 AM in NFL Picks

=14.0ptThe Buffalo Bills are going to be sitting majority of their starters in this meaningless game against the New England Patriots. Josh Allen is slated to start the game to keep his consecutive games started streak alive but will not see more than 1-2 drives. The Patriots have had Drake Maye starting lately but he is now questionable for this contest as he is nursing a hand injury. The Bills have won 10 of their last 11 games but this one will be much different due to the lack of starters playing significant time. For the Patriots, their current losing streak has been extended to 6 games after their loss to the Chargers last week 40-7. They did play these Bills tough just 2 weeks ago when they lost 24-21 after leading 14-7 at the half. Will they be able to play up to that level again and ultimately finish the game in winning fashion? Even against Buffalo’s backups, the task will not be easy for this Patriot offense that is averaging under 19ppg over their last 3 games. Buffalo’s coach Sean McDermott has been saying they do plan on winning this game but also to remain healthy. With a Super Bowl in mind, we believe the Bills will side with staying healthy over winning the game.