Detroit Lions vs Buffalo Bills Prediction & Picks - NFL

USA - NFL

Detroit Lions
12/15/24 16:25
Buffalo Bills

Prediction:

 

Lions -2.5

-110
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 by Dan Angell | in NFL Picks

The Buffalo Bills (10-3 SU, 8-5 ATS) attempt to get back on track after their first loss in two months as they visit the Detroit Lions (12-1 SU, 9-4 ATS). The Bills couldn’t slow down the Rams, which isn’t an encouraging sign as they try to get a handle on the Lions, who own the highest-scoring offense in the NFL.

Detroit does everything well, which could be a major concern for the Bills’ weak run defense. Buffalo usually wins by forcing teams out of the run and making them beat them through the air, but it won’t be able to do that in this game. The Lions aren’t the kind of team that falls behind early; they usually put up points in a hurry and bury their opponents.

Detroit Lions vs Buffalo Bills Form

Table

Teams Pts P W L
2 Detroit Lions
0.882 17 15 2
5 Buffalo Bills
0.765 17 13 4

Detroit Lions and Buffalo Bills Latest Matches

Detroit Lions
Detroit Lions Latest matches
W W W W W W
Victories

6/6 (100%)

Defeats

0/6 (0%)

Dec 5, 2024 - NFL

Detroit Lions
34 :  31
Green Bay Packers

Nov 28, 2024 - NFL

Detroit Lions
23 :  20
Chicago Bears

Nov 24, 2024 - NFL

Indianapolis Colts
6 :  24
Detroit Lions

Nov 17, 2024 - NFL

Detroit Lions
52 :  6
Jacksonville Jaguars

Nov 10, 2024 - NFL

Houston Texans
23 :  26
Detroit Lions

Nov 3, 2024 - NFL

Green Bay Packers
14 :  24
Detroit Lions
L W W W W W
Victories

5/6 (83%)

Defeats

1/6 (17%)

Dec 5, 2024 - NFL

Detroit Lions
34 :  31
Green Bay Packers

Nov 28, 2024 - NFL

Detroit Lions
23 :  20
Chicago Bears

Nov 17, 2024 - NFL

Detroit Lions
52 :  6
Jacksonville Jaguars

Oct 27, 2024 - NFL

Detroit Lions
52 :  14
Tennessee Titans

Sep 30, 2024 - NFL

Detroit Lions
42 :  29
Seattle Seahawks

Sep 15, 2024 - NFL

Detroit Lions
16 :  20
Tampa Bay Buccaneers
W W W W W W
Victories

6/6 (100%)

Defeats

0/6 (0%)

Nov 24, 2024 - NFL

Indianapolis Colts
6 :  24
Detroit Lions

Nov 10, 2024 - NFL

Houston Texans
23 :  26
Detroit Lions

Nov 3, 2024 - NFL

Green Bay Packers
14 :  24
Detroit Lions

Oct 20, 2024 - NFL

Minnesota Vikings
29 :  31
Detroit Lions

Oct 13, 2024 - NFL

Dallas Cowboys
9 :  47
Detroit Lions

Sep 22, 2024 - NFL

Arizona Cardinals
13 :  20
Detroit Lions
Buffalo Bills
Buffalo Bills Latest matches
W W W W W L
Victories

5/6 (83%)

Defeats

1/6 (17%)

Dec 8, 2024 - NFL

Los Angeles Rams
44 :  42
Buffalo Bills

Dec 1, 2024 - NFL

Buffalo Bills
35 :  10
San Francisco 49ers

Nov 17, 2024 - NFL

Buffalo Bills
30 :  21
Kansas City Chiefs

Nov 10, 2024 - NFL

Indianapolis Colts
20 :  30
Buffalo Bills

Nov 3, 2024 - NFL

Buffalo Bills
30 :  27
Miami Dolphins

Oct 27, 2024 - NFL

Seattle Seahawks
10 :  31
Buffalo Bills
W W W W W W
Victories

6/6 (100%)

Defeats

0/6 (0%)

Dec 1, 2024 - NFL

Buffalo Bills
35 :  10
San Francisco 49ers

Nov 17, 2024 - NFL

Buffalo Bills
30 :  21
Kansas City Chiefs

Nov 3, 2024 - NFL

Buffalo Bills
30 :  27
Miami Dolphins

Oct 20, 2024 - NFL

Buffalo Bills
34 :  10
Tennessee Titans

Sep 23, 2024 - NFL

Buffalo Bills
47 :  10
Jacksonville Jaguars

Sep 8, 2024 - NFL

Buffalo Bills
34 :  28
Arizona Cardinals
L L W W W L
Victories

3/6 (50%)

Defeats

3/6 (50%)

Dec 8, 2024 - NFL

Los Angeles Rams
44 :  42
Buffalo Bills

Nov 10, 2024 - NFL

Indianapolis Colts
20 :  30
Buffalo Bills

Oct 27, 2024 - NFL

Seattle Seahawks
10 :  31
Buffalo Bills

Oct 14, 2024 - NFL

New York Jets
20 :  23
Buffalo Bills

Oct 6, 2024 - NFL

Houston Texans
23 :  20
Buffalo Bills

Sep 29, 2024 - NFL

Baltimore Ravens
35 :  10
Buffalo Bills

Detroit Lions - Buffalo Bills Key Points

  1. The Bills have won four straight meetings with the Lions.
  2. The Lions are 2-3 ATS in their past five games.
  3. The Lions have not lost since Week 2.
  4. The Bills are 6-2 ATS in their past eight games.

Our Detroit Lions vs Buffalo Bills Prediction

The Lions have one free mistake in their pockets, but this doesn’t seem like the spot where they’re likely to use it. Detroit has had two tough weeks in a row against division rivals Chicago and Green Bay, but they faced the Bears on a short week and the Packers on their second straight Thursday game. For this game with Buffalo, the Lions have had extra rest and should be closer to healed.

The Bills can likely score with the Lions, but there’s nothing that says they can stop Detroit. The Lions tend to do what they need to do offensively, which led to them putting up 34 points on the Packers last week in a win. In their past five home games, only Chicago managed to hold Detroit under 30 points, and Buffalo looks unlikely to change that. Our prediction for Buffalo vs. Detroit is Lions -2.5.

Prediction:

 

Lions -2.5

-110
$350 offered for betting!

All tips are fully researched and given in good faith, but profits cannot be guaranteed.

Detroit Lions vs Buffalo Bills Picks