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by Carlos Zabala in MLB Picks
The Red Sox will fight for the remaining month of the MLB regular season to maintain their wild card spot and, if possible, to take the Yankees' spot as the #1 wild card. On Friday, both the Red Sox and Yankees lost ground to Toronto for the division lead. While the Red Sox lost in the desert to the D-backs, the Yankees lost once again in the Bronx to the Blue Jays.
The Red Sox had already lost the final game of the series against the Guardians on Thursday, 1-8 at Fenway. Cora used a bullpen game in that game that didn't go entirely well, with Jordan Hicks injuring his shoulder, but he still allowed four earned runs to the Guards in the loss. Cora did this to give star rookie Payton Toyle an extra day of rest to start the first game in the desert against the D-backs.
Toyle didn't fare as well in his second MLB start as his first. He started a game where the Red Sox were -135 favorites to win on the road at Chase Field, but he allowed two home runs and five runs, and Cora was cut short after three innings.
Even so, it was a close game that didn't break until the eighth inning in favor of the D-backs. On Saturday, the Red Sox are again listed as betting favorites in the Giolito-Pfaadt pitching duel.
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Boston Red Sox vs Arizona Diamondbacks Form
Table
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0.549 | 142 | 78 | 64 |
17
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0.5 | 142 | 71 | 71 |
Boston Red Sox and Arizona Diamondbacks Latest Matches

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Boston Red Sox against Arizona Diamondbacks : Head to Head (H2H)
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Boston Red Sox - Arizona Diamondbacks Key Points
- Both the Red Sox and D-backs are averaging 4.9 runs per game in 2025
- The Red Sox's starting pitching ERA is 4.85 this season
- In their last 10 games, the D-backs are averaging 8.4 hits per game
- Red Sox's FLD%, second-worst in MLB
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Our Boston Red Sox vs Arizona Diamondbacks Prediction
As for the Red Sox's electric, tight-knit, and young lineup, it's obvious they've had an exceptional second half, but they've suffered a bigger blow following the injury to Roman Anthony, who is unlikely to return for the remainder of the season.
For the Red Sox, Bregman went 2-for-4 with a pair of RBIs and two hits on Friday, while Refsnyder also hit another RBI double in the loss.
This D-backs team will look to fight until the end. Despite parting ways with key players at the final trade deadline, they retained Carroll. He hit the three-run homer that led off the game for Arizona on Friday. Vargas and Perdomo also homered.
Our prediction for Red Sox vs Diamondbacks is: Over 8.5 runs.
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