Aryna Sabalenka vs Amanda Anisimova Prediction & Picks - WTA US Open

Prediction published on 9/6/25, 1:14 PM  by Lou Aguila in Tennis Picks

Amanda Anisimova is 6-3 against the world’s No.1 Aryna Sabalenka in their head-to-head series ahead of Saturday’s US Open championship match in Flushing Meadows, New York.

Will Anismova, a +172 underdog, win her first Grand Slam title just months after her forgetful Wimbledon Open final meltdown?

Current Form:

Anisimova secured her second consecutive Grand Slam final appearance after coming back from a set down to beat Naomi Osaka in the semifinal 6-7(4) 7-6(3) 6-3. Anisimova displayed exceptional mental strength and grit to recover from a devastating tiebreaker loss in the first set and win the match against the four-time Grand Slam champion. With the victory, Anisimova defeated two previous US Open winners in back-to-back matches as she also exacted her revenge on Iga Swiatek 6-4 6-3 in the quarterfinal.

Sabalenka also booked her spot in the US Open women’s singles championship match for a third consecutive year after outlasting Jessica Pegula 4-6 6-3 6-4. Sabalenka dropped the first set, but she came back roaring, firing marvelous winners and simply overpowering Pegula with a barrage of massive forehands. Against Anisimova, Sabalenka gets an opportunity to avenge her loss to the American in the semifinal of the 2025 Wimbledon Open, 6-4 4-6 6-4.