Iowa State Cyclones vs Arizona Wildcats Prediction & Picks - NCAA

Prediction published on 9/27/25, 3:05 PM  by Travis Pulver | Modified on 9/30/25 at 11:20 AM in NCAA Picks

The Arizona Wildcats will travel to Iowa to face the No. 14 Iowa State Cyclones (4-0) at Jack Trice Stadium in Ames, IA. Kickoff for this Big 12 battle of undefeated teams is scheduled for 7 p.m. EST. The game will be broadcast on ESPN.

Expectations were certainly high for the Cyclones coming into the season after Iowa State made it to the Big 12 title game last season and beat Miami in the Pop-Tarts Bowl. So far, they have lived up to them. Known for often being one of the stronger defensive teams in the nation, the Cyclones have been picking it up on offense behind the leadership of junior quarterback Rocco Becht.  Becht has completed 65% of his passes so far this season with seven touchdown passes and just one interception. As for Arizona, the Wildcats go off to a solid start this season with a 40-6 win over Hawaii, followed by a dominant 48-3 showing against Weber State. They last played against Kansas State a couple of weeks ago. They used a strong run game and dominant defensive play to secure a 23-17 win with Ismal Mahdi running for 189 yards and quarterback Noah Fifita adding another 48 yards and two touchdowns on the ground.