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by Carlos Zabala in MLB Picks
D-backs right-hander Brandon Pfaadt held off an inspired Red Sox offense very well in his last outing in the desert. Pfaadt dominated them for six innings in a quality outing, striking out seven, in a game Arizona won 5-1. Now, even though the D-backs won their last game against the Giants 5-3, they need Pfaadt to be at his best on Friday in the first game of the series against the Twins in Minneapolis.
Pfaadt has a 5.18 ERA, but has received good support from the D-backs' offense and has a solid 13-8 record.
For the Twins, Venezuelan Pablo López will pitch, whose season was cut short for three months by a shoulder injury. López is one of the valuable pieces the Twins didn't part with at the trade deadline. In his return from his lengthy injury, he came prepared to go deep, and he did, throwing 92 pitches in a quality performance against the Royals.
Despite a bad September, where they lost their first six games and haven't won a series, Minnesota is the -130 betting favorite.
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Arizona Diamondbacks vs Minnesota Twins Form
Table
Teams | % | P | W | L |
---|---|---|---|---|
18
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0.497 | 147 | 73 | 74 |
26
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0.438 | 146 | 64 | 82 |
Arizona Diamondbacks and Minnesota Twins Latest Matches

3/6 (50%)
3/6 (50%)
Sep 10, 2025 - MLB
Sep 9, 2025 - MLB
Sep 8, 2025 - MLB
Sep 7, 2025 - MLB
Sep 6, 2025 - MLB
Sep 5, 2025 - MLB
4/6 (67%)
2/6 (33%)
Sep 7, 2025 - MLB
Sep 6, 2025 - MLB
Sep 5, 2025 - MLB
Sep 3, 2025 - MLB
Sep 2, 2025 - MLB
Sep 1, 2025 - MLB
3/6 (50%)
3/6 (50%)
Sep 10, 2025 - MLB
Sep 9, 2025 - MLB
Sep 8, 2025 - MLB
Aug 31, 2025 - MLB
Aug 30, 2025 - MLB
Aug 29, 2025 - MLB

2/6 (33%)
4/6 (67%)
Sep 10, 2025 - MLB
Sep 9, 2025 - MLB
Sep 8, 2025 - MLB
Sep 7, 2025 - MLB
Sep 6, 2025 - MLB
Sep 5, 2025 - MLB
1/6 (17%)
5/6 (83%)
Sep 4, 2025 - MLB
Sep 3, 2025 - MLB
Sep 2, 2025 - MLB
Sep 1, 2025 - MLB
Aug 31, 2025 - MLB
Aug 30, 2025 - MLB
2/6 (33%)
4/6 (67%)
Sep 10, 2025 - MLB
Sep 9, 2025 - MLB
Sep 8, 2025 - MLB
Sep 7, 2025 - MLB
Sep 6, 2025 - MLB
Sep 5, 2025 - MLB
Arizona Diamondbacks against Minnesota Twins : Head to Head (H2H)
33 %
67 %
Jun 27, 2024 - MLB
Jun 26, 2024 - MLB
Jun 25, 2024 - MLB
Arizona Diamondbacks - Minnesota Twins Key Points
- The Twins have won five of their last six games against the D-backs
- The Diamondbacks are producing 4.9 runs per game this season
- The Twins' record this season is 2-8 in their last 10 games
- Jeffers is injured by the Twins, and Marte and Gurriel are injured by the D-backs
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Our Arizona Diamondbacks vs Minnesota Twins Prediction
The D-backs are missing two of their best bats due to injuries. Corbin Carroll, who went 0-for-3, was absent in Wednesday's loss to the Giants. However, designated hitter Del Castillo had an even worse day, going 0-for-5 with four strikeouts.
This year's stats for the Twins' home-batting performance show a significant decline. At target field in 2025, the Twins have a collective AVG of 229.
If Pfaadt and López appear at their best, a low-run game seems likely.
Our prediction for Diamondbacks vs Twins is: Under 8.5 runs.
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