Arizona Diamondbacks vs Minnesota Twins Prediction & Picks - MLB

USA - MLB

Arizona Diamondbacks
9/12/25 20:10
Minnesota Twins

Prediction:

 

Under 8.5

-119
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 by Carlos Zabala in MLB Picks

D-backs right-hander Brandon Pfaadt held off an inspired Red Sox offense very well in his last outing in the desert. Pfaadt dominated them for six innings in a quality outing, striking out seven, in a game Arizona won 5-1. Now, even though the D-backs won their last game against the Giants 5-3, they need Pfaadt to be at his best on Friday in the first game of the series against the Twins in Minneapolis.

Pfaadt has a 5.18 ERA, but has received good support from the D-backs' offense and has a solid 13-8 record.

For the Twins, Venezuelan Pablo López will pitch, whose season was cut short for three months by a shoulder injury. López is one of the valuable pieces the Twins didn't part with at the trade deadline. In his return from his lengthy injury, he came prepared to go deep, and he did, throwing 92 pitches in a quality performance against the Royals.

Despite a bad September, where they lost their first six games and haven't won a series, Minnesota is the -130 betting favorite.

Arizona Diamondbacks vs Minnesota Twins Form

Table

Teams % P W L
18
Arizona Diamondbacks
Arizona Diamondbacks
0.497 147 73 74
26
Minnesota Twins
Minnesota Twins
0.438 146 64 82

Arizona Diamondbacks and Minnesota Twins Latest Matches

Arizona Diamondbacks
Arizona Diamondbacks Latest matches
W L W L L W
Victories

3/6 (50%)

Defeats

3/6 (50%)

Sep 10, 2025 - MLB

Arizona Diamondbacks
5 :  3
San Francisco Giants

Sep 9, 2025 - MLB

Arizona Diamondbacks
3 :  5
San Francisco Giants

Sep 8, 2025 - MLB

Arizona Diamondbacks
5 :  11
San Francisco Giants

Sep 7, 2025 - MLB

Boston Red Sox
7 :  4
Arizona Diamondbacks

Sep 6, 2025 - MLB

Boston Red Sox
1 :  5
Arizona Diamondbacks

Sep 5, 2025 - MLB

Boston Red Sox
5 :  10
Arizona Diamondbacks
L W W W L W
Victories

4/6 (67%)

Defeats

2/6 (33%)

Sep 7, 2025 - MLB

Boston Red Sox
7 :  4
Arizona Diamondbacks

Sep 6, 2025 - MLB

Boston Red Sox
1 :  5
Arizona Diamondbacks

Sep 5, 2025 - MLB

Boston Red Sox
5 :  10
Arizona Diamondbacks

Sep 3, 2025 - MLB

Texas Rangers
0 :  2
Arizona Diamondbacks

Sep 2, 2025 - MLB

Texas Rangers
3 :  5
Arizona Diamondbacks

Sep 1, 2025 - MLB

Texas Rangers
7 :  5
Arizona Diamondbacks
W L W L L W
Victories

3/6 (50%)

Defeats

3/6 (50%)

Sep 10, 2025 - MLB

Arizona Diamondbacks
5 :  3
San Francisco Giants

Sep 9, 2025 - MLB

Arizona Diamondbacks
3 :  5
San Francisco Giants

Sep 8, 2025 - MLB

Arizona Diamondbacks
5 :  11
San Francisco Giants

Aug 31, 2025 - MLB

Arizona Diamondbacks
4 :  5
Los Angeles Dodgers

Aug 30, 2025 - MLB

Arizona Diamondbacks
6 :  1
Los Angeles Dodgers

Aug 29, 2025 - MLB

Arizona Diamondbacks
3 :  0
Los Angeles Dodgers
Minnesota Twins
Minnesota Twins Latest matches
L L W W L L
Victories

2/6 (33%)

Defeats

4/6 (67%)

Sep 10, 2025 - MLB

Minnesota Twins
3 :  4
Los Angeles Angels

Sep 9, 2025 - MLB

Minnesota Twins
2 :  12
Los Angeles Angels

Sep 8, 2025 - MLB

Minnesota Twins
12 :  3
Los Angeles Angels

Sep 7, 2025 - MLB

Minnesota Twins
5 :  1
Kansas City Royals

Sep 6, 2025 - MLB

Minnesota Twins
2 :  11
Kansas City Royals

Sep 5, 2025 - MLB

Minnesota Twins
1 :  2
Kansas City Royals
W W L L L L
Victories

1/6 (17%)

Defeats

5/6 (83%)

Sep 4, 2025 - MLB

Chicago White Sox
11 :  8
Minnesota Twins

Sep 3, 2025 - MLB

Chicago White Sox
4 :  3
Minnesota Twins

Sep 2, 2025 - MLB

Chicago White Sox
12 :  3
Minnesota Twins

Sep 1, 2025 - MLB

Chicago White Sox
6 :  5
Minnesota Twins

Aug 31, 2025 - MLB

San Diego Padres
2 :  7
Minnesota Twins

Aug 30, 2025 - MLB

San Diego Padres
12 :  3
Minnesota Twins
L L W W L L
Victories

2/6 (33%)

Defeats

4/6 (67%)

Sep 10, 2025 - MLB

Minnesota Twins
3 :  4
Los Angeles Angels

Sep 9, 2025 - MLB

Minnesota Twins
2 :  12
Los Angeles Angels

Sep 8, 2025 - MLB

Minnesota Twins
12 :  3
Los Angeles Angels

Sep 7, 2025 - MLB

Minnesota Twins
5 :  1
Kansas City Royals

Sep 6, 2025 - MLB

Minnesota Twins
2 :  11
Kansas City Royals

Sep 5, 2025 - MLB

Minnesota Twins
1 :  2
Kansas City Royals

Arizona Diamondbacks against Minnesota Twins : Head to Head (H2H)

Arizona Diamondbacks

33 %

Minnesota Twins

67 %

Jun 27, 2024 - MLB

Minnesota Twins
13 :  6
Arizona Diamondbacks

Jun 26, 2024 - MLB

Minnesota Twins
8 :  3
Arizona Diamondbacks

Jun 25, 2024 - MLB

Minnesota Twins
4 :  5
Arizona Diamondbacks

Arizona Diamondbacks - Minnesota Twins Key Points

  1. The Twins have won five of their last six games against the D-backs
  2. The Diamondbacks are producing 4.9 runs per game this season
  3. The Twins' record this season is 2-8 in their last 10 games
  4. Jeffers is injured by the Twins, and Marte and Gurriel are injured by the D-backs

Our Arizona Diamondbacks vs Minnesota Twins Prediction

The D-backs are missing two of their best bats due to injuries. Corbin Carroll, who went 0-for-3, was absent in Wednesday's loss to the Giants. However, designated hitter Del Castillo had an even worse day, going 0-for-5 with four strikeouts.

This year's stats for the Twins' home-batting performance show a significant decline. At target field in 2025, the Twins have a collective AVG of 229.

If Pfaadt and López appear at their best, a low-run game seems likely.

Our prediction for Diamondbacks vs Twins is: Under 8.5 runs.

Prediction:

 

Under 8.5

-119
$400+ offered for betting!

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Arizona Diamondbacks vs Minnesota Twins Picks