Tampa Bay Buccaneers vs Arizona Cardinals Prediction & Picks - NFL

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Tampa Bay Buccaneers
11/30/25 13:00
Arizona Cardinals

Prediction:

 

Buccaneers ML

-197
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 by Travis Pulver | in NFL Picks

The Tampa Bay Buccaneers will try to end their three-game slide when they host the Arizona Cardinals at Raymond James Stadium in Tampa, FL. Kickoff is scheduled for 1 p.m. EST, and the game will be broadcast on Fox.

A few weeks ago, the Buccaneers appeared to be in complete control of the NFC South, but fast forward three weeks—and three losses – and they are fighting to stay on top with the Carolina Panthers nipping at their heels. This harsh reality may have something to do with Baker Mayfield playing despite leaving the game last week with a shoulder injury. Arizona’s defense is ranked 22nd in the league in sacks with 22; Tampa Bay’s offensive line has given up 24 this season. As for the Cardinals, Arizona‘s passing game has thrived with Jacoby Brissett behind center, averaging over 300 yards a game in the last six. However, with the run game struggling to gain traction (they have not had a 100-yard rusher this season), the passing game has kept them competitive. But despite Brissett’s big numbers, the Cardinals are 1-5 in those games. Why? Because the defense can’t stop anyone (No. 19 in total yards; No. 25 in scoring).

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Tampa Bay Buccaneers vs Arizona Cardinals Form

Table

Teams Pts P W L
16 Tampa Bay Buccaneers
0.471 17 8 9
30 Arizona Cardinals
0.176 17 3 14

Tampa Bay Buccaneers and Arizona Cardinals Latest Matches

Tampa Bay Buccaneers
Tampa Bay Buccaneers Latest matches
W L W L L L
Victories

2/6 (33%)

Defeats

4/6 (67%)

Nov 23, 2025 - NFL

Los Angeles Rams
34 :  7
Tampa Bay Buccaneers

Nov 16, 2025 - NFL

Buffalo Bills
44 :  32
Tampa Bay Buccaneers

Nov 9, 2025 - NFL

Tampa Bay Buccaneers
23 :  28
New England Patriots

Oct 26, 2025 - NFL

New Orleans Saints
3 :  23
Tampa Bay Buccaneers

Oct 20, 2025 - NFL

Detroit Lions
24 :  9
Tampa Bay Buccaneers

Oct 12, 2025 - NFL

Tampa Bay Buccaneers
30 :  19
San Francisco 49ers
W L W L W L
Victories

3/6 (50%)

Defeats

3/6 (50%)

Nov 9, 2025 - NFL

Tampa Bay Buccaneers
23 :  28
New England Patriots

Oct 12, 2025 - NFL

Tampa Bay Buccaneers
30 :  19
San Francisco 49ers

Sep 28, 2025 - NFL

Tampa Bay Buccaneers
25 :  31
Philadelphia Eagles

Sep 21, 2025 - NFL

Tampa Bay Buccaneers
29 :  27
New York Jets

Jan 12, 2025 - NFL

Tampa Bay Buccaneers
20 :  23
Washington Commanders

Jan 5, 2025 - NFL

Tampa Bay Buccaneers
27 :  19
New Orleans Saints
W W L W L L
Victories

3/6 (50%)

Defeats

3/6 (50%)

Nov 23, 2025 - NFL

Los Angeles Rams
34 :  7
Tampa Bay Buccaneers

Nov 16, 2025 - NFL

Buffalo Bills
44 :  32
Tampa Bay Buccaneers

Oct 26, 2025 - NFL

New Orleans Saints
3 :  23
Tampa Bay Buccaneers

Oct 20, 2025 - NFL

Detroit Lions
24 :  9
Tampa Bay Buccaneers

Oct 5, 2025 - NFL

Seattle Seahawks
35 :  38
Tampa Bay Buccaneers

Sep 15, 2025 - NFL

Houston Texans
19 :  20
Tampa Bay Buccaneers
Arizona Cardinals
Arizona Cardinals Latest matches
L L W L L L
Victories

1/6 (17%)

Defeats

5/6 (83%)

Nov 23, 2025 - NFL

Arizona Cardinals
24 :  27
Jacksonville Jaguars

Nov 16, 2025 - NFL

Arizona Cardinals
22 :  41
San Francisco 49ers

Nov 9, 2025 - NFL

Seattle Seahawks
44 :  22
Arizona Cardinals

Nov 3, 2025 - NFL

Dallas Cowboys
17 :  27
Arizona Cardinals

Oct 19, 2025 - NFL

Arizona Cardinals
23 :  27
Green Bay Packers

Oct 12, 2025 - NFL

Indianapolis Colts
31 :  27
Arizona Cardinals
W L L L L L
Victories

1/6 (17%)

Defeats

5/6 (83%)

Nov 23, 2025 - NFL

Arizona Cardinals
24 :  27
Jacksonville Jaguars

Nov 16, 2025 - NFL

Arizona Cardinals
22 :  41
San Francisco 49ers

Oct 19, 2025 - NFL

Arizona Cardinals
23 :  27
Green Bay Packers

Oct 5, 2025 - NFL

Arizona Cardinals
21 :  22
Tennessee Titans

Sep 25, 2025 - NFL

Arizona Cardinals
20 :  23
Seattle Seahawks

Sep 14, 2025 - NFL

Arizona Cardinals
27 :  22
Carolina Panthers
L W L L W L
Victories

2/6 (33%)

Defeats

4/6 (67%)

Nov 9, 2025 - NFL

Seattle Seahawks
44 :  22
Arizona Cardinals

Nov 3, 2025 - NFL

Dallas Cowboys
17 :  27
Arizona Cardinals

Oct 12, 2025 - NFL

Indianapolis Colts
31 :  27
Arizona Cardinals

Sep 21, 2025 - NFL

San Francisco 49ers
16 :  15
Arizona Cardinals

Sep 7, 2025 - NFL

New Orleans Saints
13 :  20
Arizona Cardinals

Dec 28, 2024 - NFL

Los Angeles Rams
13 :  9
Arizona Cardinals

Tampa Bay Buccaneers - Arizona Cardinals Key Points

  1. The all-time series between Arizona and Tampa Bay is tied at 11 wins apiece.
  2. Tampa Bay won the last meeting on Christmas Day in 2022, 19-16 in OT, but the Cardinals have won three of the last five games.
  3. The Cardinals are 1-8 SU and 3-6 ATS in their last nine games.
  4. Betting Public: 86% of moneyline tickets and 90% of the handle are on the Buccaneers.
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Our Tampa Bay Buccaneers vs Arizona Cardinals Prediction

Tampa Bay is the better overall team between the two, but I’m a bit concerned about whether Mayfield will be physical enough to make the plays the Bucs will need to in order to win this game. He's the kind of warrior who will want to play no matter what, and after what we saw last week from Teddy Bridgewater, they'll let him go if he says he can play. Brissett is going to throw for some serious yards on the Bucs' leaky pass defense. So, can we trust the Bucs to win? I think so, but I am not confident they’ll cover.

Our Arizona vs. Tampa Bay Pick: Buccaneers ML

Prediction:

 

Buccaneers ML

-197
$250 offered for betting!

All tips are fully researched and given in good faith, but profits cannot be guaranteed.

Tampa Bay Buccaneers vs Arizona Cardinals Picks