New Orleans Saints vs Arizona Cardinals Prediction & Picks - NFL

USA - NFL

New Orleans Saints
9/7/25 13:00
Arizona Cardinals

Prediction:

 

Under 43.5 Total Points

-112
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 by Matt Lowrimore | in NFL Picks

Week 1 of the NFL is finally here, and with that, one of the matchups on the Sunday slate will see the New Orleans Saints take on the Arizona Cardinals. Let’s take a look at the match statistics and predictions for this game between the Saints and Cardinals.

Arizona enters this game coming off an 8-9 record in 2024-2025. The Cardinals finished in third place in the NFC West division, and it was the third straight season that Arizona has missed the playoffs.

As for New Orleans, they are coming off a disastrous 2024-2025 season in which they finished with a record of 5-12. The Saints finished in fourth place in the NFC South division and have now missed the playoffs for four straight years. The Saints welcome in a new head coach for the 2025-2026 season, that being Kellen Moore, in the hopes that he can lead them back to their winning ways.

New Orleans Saints vs Arizona Cardinals Form

Table

Teams Pts P W L
25 New Orleans Saints
0.353 17 6 11
30 Arizona Cardinals
0.176 17 3 14

New Orleans Saints and Arizona Cardinals Latest Matches

New Orleans Saints
New Orleans Saints Latest matches
W W L L L L
Victories

2/6 (33%)

Defeats

4/6 (67%)

Jan 5, 2025 - NFL

Tampa Bay Buccaneers
27 :  19
New Orleans Saints

Dec 29, 2024 - NFL

New Orleans Saints
10 :  25
Las Vegas Raiders

Dec 23, 2024 - NFL

Green Bay Packers
34 :  0
New Orleans Saints

Dec 15, 2024 - NFL

New Orleans Saints
19 :  20
Washington Commanders

Dec 8, 2024 - NFL

New York Giants
11 :  14
New Orleans Saints

Nov 17, 2024 - NFL

New Orleans Saints
35 :  14
Cleveland Browns
L L W W L L
Victories

2/6 (33%)

Defeats

4/6 (67%)

Dec 29, 2024 - NFL

New Orleans Saints
10 :  25
Las Vegas Raiders

Dec 15, 2024 - NFL

New Orleans Saints
19 :  20
Washington Commanders

Nov 17, 2024 - NFL

New Orleans Saints
35 :  14
Cleveland Browns

Nov 10, 2024 - NFL

New Orleans Saints
20 :  17
Atlanta Falcons

Oct 17, 2024 - NFL

New Orleans Saints
10 :  33
Denver Broncos

Oct 13, 2024 - NFL

New Orleans Saints
27 :  51
Tampa Bay Buccaneers
L L L W L L
Victories

1/6 (17%)

Defeats

5/6 (83%)

Jan 5, 2025 - NFL

Tampa Bay Buccaneers
27 :  19
New Orleans Saints

Dec 23, 2024 - NFL

Green Bay Packers
34 :  0
New Orleans Saints

Dec 8, 2024 - NFL

New York Giants
11 :  14
New Orleans Saints

Nov 3, 2024 - NFL

Carolina Panthers
23 :  22
New Orleans Saints

Oct 27, 2024 - NFL

Los Angeles Chargers
26 :  8
New Orleans Saints

Oct 7, 2024 - NFL

Kansas City Chiefs
26 :  13
New Orleans Saints
Arizona Cardinals
Arizona Cardinals Latest matches
L L W L L W
Victories

2/6 (33%)

Defeats

4/6 (67%)

Jan 5, 2025 - NFL

Arizona Cardinals
47 :  24
San Francisco 49ers

Dec 28, 2024 - NFL

Los Angeles Rams
13 :  9
Arizona Cardinals

Dec 22, 2024 - NFL

Carolina Panthers
36 :  30
Arizona Cardinals

Dec 15, 2024 - NFL

Arizona Cardinals
30 :  17
New England Patriots

Dec 8, 2024 - NFL

Arizona Cardinals
18 :  30
Seattle Seahawks

Dec 1, 2024 - NFL

Minnesota Vikings
23 :  22
Arizona Cardinals
W W W L W W
Victories

5/6 (83%)

Defeats

1/6 (17%)

Jan 5, 2025 - NFL

Arizona Cardinals
47 :  24
San Francisco 49ers

Dec 15, 2024 - NFL

Arizona Cardinals
30 :  17
New England Patriots

Dec 8, 2024 - NFL

Arizona Cardinals
18 :  30
Seattle Seahawks

Nov 10, 2024 - NFL

Arizona Cardinals
31 :  6
New York Jets

Nov 3, 2024 - NFL

Arizona Cardinals
29 :  9
Chicago Bears

Oct 21, 2024 - NFL

Arizona Cardinals
17 :  15
Los Angeles Chargers
L W L L L L
Victories

1/6 (17%)

Defeats

5/6 (83%)

Dec 28, 2024 - NFL

Los Angeles Rams
13 :  9
Arizona Cardinals

Dec 22, 2024 - NFL

Carolina Panthers
36 :  30
Arizona Cardinals

Dec 1, 2024 - NFL

Minnesota Vikings
23 :  22
Arizona Cardinals

Nov 24, 2024 - NFL

Seattle Seahawks
16 :  6
Arizona Cardinals

Oct 27, 2024 - NFL

Miami Dolphins
27 :  28
Arizona Cardinals

Oct 13, 2024 - NFL

Green Bay Packers
34 :  13
Arizona Cardinals

New Orleans Saints - Arizona Cardinals Key Points

  1. Arizona was 2-6 SU on the road last season
  2. New Orleans was 3-6 SU at home last season
  3. New Orleans averaged 19.9 points per game last season
  4. Arizona averaged 23.5 points per game last season

Our New Orleans Saints vs Arizona Cardinals Prediction

This is a tricky matchup, as both teams struggled to score consistently last season. New Orleans ranked 24th in scoring offense last year, averaging just 19.9 points per game. As for Arizona, they averaged 23.5 points per game and ranked 12th.

Defensively, both the Saints and Cardinals were similar, with New Orleans allowing an average of 23.4 points per game and Arizona allowing an average of 22.2 points per game.

With this being the start of a new season and the first game for the Saints under Kellen Moore, points could be at a premium, especially on the New Orleans side. For that reason, our New Orleans Saints vs Arizona Cardinals prediction is: Under 43.5 Total Points.

Prediction:

 

Under 43.5 Total Points

-112
$200 offered for betting!

All tips are fully researched and given in good faith, but profits cannot be guaranteed.

New Orleans Saints vs Arizona Cardinals Picks