Alexei Popyrin vs Andrey Rublev Prediction & Picks - ATP Cincinnati Open

ATP - ATP Cincinnati Open

ATP 19 Australia
Alexei Popyrin
8/12/25 11:00
ATP 11 Russia
Andrey Rublev

Prediction:

 

Alexei Popyrin +2.5 Games

-115
$200 offered for betting!

New customers only | Commercial content | 21+ age limit | T&Cs apply

 by Lou Aguila | in ATP Cincinnati Open Picks

Will the +160 underdog Alexei Popyrin make three in a row against Andrey Rublev?

The Australian will attempt to sustain her mastery over the former top-10 Rublev in their upcoming third-round clash at the 2025 Cincinnati Open on Tuesday.

Popyrin made it to the round of 32 of the Cincinnati Open after Martin Landaluce of Spain 7-6(3) 6-3. Fresh off a quarterfinal run in Toronto, Popyrin sustained his impeccable form on the serve, bombarding Landaluce with 15 aces and 37 points on the first serves. The Aussie also captured two breakpoints that allowed him to get the job done in two sets.

Rublev swept Learner Tien also in straight sets 7-6(4) 6-3, avenging his earlier loss to the young American at the Citi Open. The Russian played stronger and sharper in this second matchup with Tien as he allowed only one service break while winning two breakpoints behind 30 return points. The win improved Rublev’s 2025 hard-court record to 11-8 and his overall record this year to 27-17.

Up to $200 to bet on Alexei Popyrin - Andrey Rublev! 

Limited Offer. Currently at DraftKings

Alexei Popyrin vs Andrey Rublev Form

Alexei Popyrin and Andrey Rublev Latest Matches

Alexei Popyrin Latest matches
L W W W L W
Victories

4/6 (67%)

Defeats

2/6 (33%)

Aug 10, 2025 - ATP Cincinnati Open

Alexei Popyrin
2 :  0
Martin Landaluce

Aug 4, 2025 - ATP Toronto

Alexander Zverev
2 :  1
Alexei Popyrin

Aug 2, 2025 - ATP Toronto

Alexei Popyrin
2 :  1
Holger Rune

Jul 31, 2025 - ATP Toronto

Daniil Medvedev
1 :  2
Alexei Popyrin

Jul 29, 2025 - ATP Toronto

Nicolas Arseneault
0 :  2
Alexei Popyrin

Jul 23, 2025 - ATP Washington Citi Open

Yibing Wu
2 :  1
Alexei Popyrin
Andrey Rublev Latest matches
L W W W L W
Victories

3/6 (50%)

Defeats

3/6 (50%)

Aug 10, 2025 - ATP Cincinnati Open

Learner Tien
0 :  2
Andrey Rublev

Aug 5, 2025 - ATP Toronto

Andrey Rublev
0 :  2
Taylor Fritz

Aug 3, 2025 - ATP Toronto

Andrey Rublev
abort
Alejandro Davidovich Fokina

Aug 1, 2025 - ATP Toronto

Andrey Rublev
2 :  1
Lorenzo Sonego

Jul 30, 2025 - ATP Toronto

Andrey Rublev
2 :  0
Hugo Gaston

Jul 23, 2025 - ATP Washington Citi Open

Learner Tien
2 :  0
Andrey Rublev

Alexei Popyrin against Andrey Rublev : Head to Head (H2H)

Alexei Popyrin

67 %

Andrey Rublev

33 %

Aug 12, 2024 - ATP National Bank Open

Andrey Rublev
0 :  2
Alexei Popyrin

Apr 10, 2024 - ATP Monte Carlo Masters

Alexei Popyrin
2 :  0
Andrey Rublev

Oct 24, 2023 - ATP Vienna

Alexei Popyrin
0 :  2
Andrey Rublev
Compare Alexei Popyrin and Andrey Rublev with our comparison tool.

Alexei Popyrin - Andrey Rublev Key Points

  1. Alexei Popyrin defeated Martin Landaluce 7-6(3) 6-3 in the second round of the 2025 Cincinnati Open.
  2. Alexei Popyrin is 2-1 vs. Andrey Rublev in his head-to-head chance
  3. Andrey Rublev defeated Learner Tien 7-6(4) 6-3 in the second round of the 2025 Cincinnati Open.
  4. Andrey Rublev is 11-8 on the hard court in 2025.
Up to $200 to bet on Alexei Popyrin - Andrey Rublev! 

Limited Offer. Currently at DraftKings

Our Alexei Popyrin vs Andrey Rublev Prediction

While I am no longer sure if he can win three in a row against Rublev, Popyrin might still be a firm pick to beat the spread in their match on Tuesday.

Yes, Popyrin failed to defend his Canadian Open title, but Popyrin held his own in his quarterfinal showdown with Alexander Zverev. The Aussie even took the first set before running out of steam against the world’s No.3, 6(8)-7 4-6, 3-6.

Rublev is playing probably his best stretch of tennis this year, apart from his title run in Qatar. After two straight setbacks at the hands of Popyrin, Rublev has enough motivation to end his losing streak against the Aussie. MatchStats gives Rublev a 55 percent win probability for Tuesday’s match with Popyrin, indicating a growing optimism among tennis and betting experts about the Russian’s current form.

Rublev is in terrific shape to beat Popyrin and make a deep run in this tournament. This is why he is my moneyline pick for this particular match. On the other hand, Popyrin has already proven that he can match up well with top-tier players, especially if his shots are landing down the line. Because of that, I would recommend taking Popyrin at +2.5 Games in anticipation of another thrilling matchup.

Our betting prediction for Alexei Popyrin vs. Andrey Rublev: Alexei Popyrin +2.5 Games

Prediction:

 

Alexei Popyrin +2.5 Games

-115
$200 offered for betting!

Jackpot Pools

DK Jackpot Pools

DraftKings's long-running promo Jackpot Pools gives bettors a chance to win a whopping $10,000 which grows with every entry! 

To win, you'll need to answer all 15 questions correctly and the pool is yours! If there are multiple winners, the pool will be split. If no one wins, however, the jackpot rolls over to the next pool, increasing the winnings. You can enter up to 10 times each pool to give yourself an even greater chance of winning. Once the event has completed, you can collect your winnings within 24 hours so keep an eye on the pool! Don't miss out on your chance to win big and make your picks today!

Get started today!

All tips are fully researched and given in good faith, but profits cannot be guaranteed.

Alexei Popyrin vs Andrey Rublev Picks
Up to $200 to bet on Alexei Popyrin - Andrey Rublev! 

Limited Offer. Currently at DraftKings