South Carolina Gamecocks vs Alabama Crimson Tide Prediction & Picks - NCAA

USA - NCAA

South Carolina Gamecocks
10/25/25 15:30
Alabama Crimson Tide

Prediction:

 

Alabama -11

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 by Travis Pulver | in NCAA Picks

The Alabama Crimson Tide will try to remain undefeated in SEC play this weekend when they travel to Columbia, SC, to face the South Carolina Gamecocks at Williams-Brice Stadium. Kickoff is scheduled for 3:30 p.m. EST, and the game will be broadcast on ABC.

After getting embarrassed by Florida State in the season opener, 31-17, the outlook was cloudy for the Crimson Tide. But a six-game winning streak that includes four in a row against ranked teams has done away with any doubts about the Tide. The run game isn’t what it was in the Saban Era, but Ty Simpson has the passing game clicking and averaging close to 300 yards per game. Their pass defense is ranked 10th in the country, allowing 154.6 yards per game. Incidentally, that is also how many rushing yards they allow per game (83rd in the nation). As for South Carolina, the offense has had some issues this season. It is ranked outside of the top 100 teams in the country in total yards (297.7 ypg), rushing yards (106.6 ypg), passing yards (191.1 ypg),  and points (20.1 ppg). But their pass defense is holding teams to under 200 yards per game (No. 29) and just 20 points per game.

South Carolina Gamecocks vs Alabama Crimson Tide Form

Table

South Carolina Gamecocks and Alabama Crimson Tide Latest Matches

South Carolina Gamecocks
South Carolina Gamecocks Latest matches
W L L W L L
Victories

2/6 (33%)

Defeats

4/6 (67%)

Oct 18, 2025 - NCAA

South Carolina Gamecocks
7 :  26
Oklahoma Sooners

Oct 11, 2025 - NCAA

LSU Tigers
20 :  10
South Carolina Gamecocks

Sep 27, 2025 - NCAA

South Carolina Gamecocks
35 :  13
Kentucky Wildcats

Sep 20, 2025 - NCAA

Missouri Tigers
29 :  20
South Carolina Gamecocks

Sep 13, 2025 - NCAA

South Carolina Gamecocks
7 :  31
Vanderbilt Commodores

Sep 6, 2025 - NCAA

South Carolina Gamecocks
38 :  10
South Carolina State Bulldogs
L W W L W L
Victories

3/6 (50%)

Defeats

3/6 (50%)

Oct 18, 2025 - NCAA

South Carolina Gamecocks
7 :  26
Oklahoma Sooners

Sep 27, 2025 - NCAA

South Carolina Gamecocks
35 :  13
Kentucky Wildcats

Sep 13, 2025 - NCAA

South Carolina Gamecocks
7 :  31
Vanderbilt Commodores

Sep 6, 2025 - NCAA

South Carolina Gamecocks
38 :  10
South Carolina State Bulldogs

Aug 31, 2025 - NCAA

South Carolina Gamecocks
24 :  11
Virginia Tech Hokies

Sep 14, 2024 - NCAA

South Carolina Gamecocks
33 :  36
LSU Tigers
W L L
Victories

1/3 (33%)

Defeats

2/3 (67%)

Oct 11, 2025 - NCAA

LSU Tigers
20 :  10
South Carolina Gamecocks

Sep 20, 2025 - NCAA

Missouri Tigers
29 :  20
South Carolina Gamecocks

Oct 19, 2024 - NCAA

Oklahoma Sooners
9 :  35
South Carolina Gamecocks
Alabama Crimson Tide
Alabama Crimson Tide Latest matches
W W W W W W
Victories

6/6 (100%)

Defeats

0/6 (0%)

Oct 18, 2025 - NCAA

Alabama Crimson Tide
37 :  20
Tennessee Volunteers

Oct 11, 2025 - NCAA

Missouri Tigers
24 :  27
Alabama Crimson Tide

Oct 4, 2025 - NCAA

Alabama Crimson Tide
30 :  14
Vanderbilt Commodores

Sep 27, 2025 - NCAA

Georgia Bulldogs
21 :  24
Alabama Crimson Tide

Sep 13, 2025 - NCAA

Alabama Crimson Tide
38 :  14
Wisconsin Badgers

Sep 6, 2025 - NCAA

Alabama Crimson Tide
73 :  0
Louisiana-Monroe Warhawks
W W W W W W
Victories

6/6 (100%)

Defeats

0/6 (0%)

Oct 18, 2025 - NCAA

Alabama Crimson Tide
37 :  20
Tennessee Volunteers

Oct 4, 2025 - NCAA

Alabama Crimson Tide
30 :  14
Vanderbilt Commodores

Sep 13, 2025 - NCAA

Alabama Crimson Tide
38 :  14
Wisconsin Badgers

Sep 6, 2025 - NCAA

Alabama Crimson Tide
73 :  0
Louisiana-Monroe Warhawks

Sep 28, 2024 - NCAA

Alabama Crimson Tide
41 :  34
Georgia Bulldogs

Sep 7, 2024 - NCAA

Alabama Crimson Tide
42 :  16
South Florida Bulls
W L W W
Victories

3/4 (75%)

Defeats

1/4 (25%)

Oct 11, 2025 - NCAA

Missouri Tigers
24 :  27
Alabama Crimson Tide

Sep 27, 2025 - NCAA

Georgia Bulldogs
21 :  24
Alabama Crimson Tide

Aug 30, 2025 - NCAA

Florida State Seminoles
31 :  17
Alabama Crimson Tide

Sep 14, 2024 - NCAA

Wisconsin Badgers
10 :  42
Alabama Crimson Tide

South Carolina Gamecocks - Alabama Crimson Tide Key Points

  1. Alabama leads the all-time series vs. South Carolina 14-3.
  2. South Carolina last beat Alabama in Columbia in 2010, 35-21.
  3. Alabama is 5-1-1 ATS this season; South Carolina is 3-4.
  4. Betting Public: 83.5% of spread tickets and 84% of the handle are on Alabama.

Our South Carolina Gamecocks vs Alabama Crimson Tide Prediction

If this were Week 2, I’d say give some thought to South Carolina making a game of it. In a 24-11 win over Virginia Tech. They looked good but not great on both sides of the ball, while Alabama looked mortal against Florida State. Fast forward to the present, and this looks like another easy one for the Tide. Alabama’s defense is playing well, and Ty Simpson has the offense clicking. South Carolina, on the other hand, has dealt with several injuries and enters this game 1-4 in SEC play. SC QB Lanoris Sellers is fun to watch, but he needs help for this Gamecocks team to compete with Bama. But he’s not going to get it.

Our Alabama vs. South Carolina Pick: Alabama -11

Prediction:

 

Alabama -11

-110
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South Carolina Gamecocks vs Alabama Crimson Tide Picks