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by Lou Aguila in MLB Picks
The Pittsburgh Pirates will try to capture their third win in their last four games on Monday as they tussle with the St. Louis Cardinals in Wednesday’s Game 3 at PNC Park.
The Pirates’ two-game winning streak snapped after bowing to the Cardinals, 3-5, in Game 2. Paul Skenes probably had his worst outing since playing in the Majors, allowing five earned runs and six hits over six innings. Skenes’ troublesome night on the mound on Tuesday has further compounded the Pirates’ pitching woes this season as the club holds the fourth worst ERA in baseball at 4.90.
The Cardinals, meanwhile, bagged their first win in five games behind a robust production from their batting corps. Victor Scott II delivered a two-run triple to ignite a three-run rally in the third inning. Pedro Pages and Alec Burleson drove one run each in the 6th inning, prompting the Pirates coaching staff to conclude Skenes’ worst outing in the MLB.
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St. Louis Cardinals vs Pittsburgh Pirates Form
Table
Teams | % | P | W | L |
---|---|---|---|---|
22
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0.438 | 32 | 14 | 18 |
28
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0.375 | 32 | 12 | 20 |
St. Louis Cardinals and Pittsburgh Pirates Latest Matches

2/6 (33%)
4/6 (67%)
Apr 8, 2025 - MLB
Apr 7, 2025 - MLB
Apr 6, 2025 - MLB
Apr 6, 2025 - MLB
Apr 4, 2025 - MLB
Apr 2, 2025 - MLB
4/6 (67%)
2/6 (33%)
Apr 2, 2025 - MLB
Apr 1, 2025 - MLB
Mar 31, 2025 - MLB
Mar 30, 2025 - MLB
Mar 29, 2025 - MLB
Mar 27, 2025 - MLB
2/6 (33%)
4/6 (67%)
Apr 8, 2025 - MLB
Apr 7, 2025 - MLB
Apr 6, 2025 - MLB
Apr 6, 2025 - MLB
Apr 4, 2025 - MLB
Mar 24, 2025 - MLB Spring Training

3/6 (50%)
3/6 (50%)
Apr 8, 2025 - MLB
Apr 7, 2025 - MLB
Apr 6, 2025 - MLB
Apr 5, 2025 - MLB
Apr 4, 2025 - MLB
Apr 2, 2025 - MLB
2/6 (33%)
4/6 (67%)
Apr 8, 2025 - MLB
Apr 7, 2025 - MLB
Apr 6, 2025 - MLB
Apr 5, 2025 - MLB
Apr 4, 2025 - MLB
Mar 22, 2025 - MLB Spring Training
2/6 (33%)
4/6 (67%)
Apr 2, 2025 - MLB
Apr 1, 2025 - MLB
Mar 31, 2025 - MLB
Mar 30, 2025 - MLB
Mar 29, 2025 - MLB
Mar 28, 2025 - MLB
St. Louis Cardinals against Pittsburgh Pirates : Head to Head (H2H)
67 %
33 %
Apr 8, 2025 - MLB
Apr 7, 2025 - MLB
Sep 19, 2024 - MLB
Sep 18, 2024 - MLB
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Sep 16, 2024 - MLB
St. Louis Cardinals - Pittsburgh Pirates Key Points
- The total has gone OVER in 5 of Pittsburgh's last 5 games.
- The total has gone OVER in 5 of Pittsburgh's last 6 games at home.
- The total has gone OVER in 8 of St. Louis' last 9 games.
- The total has gone OVER in 4 of St. Louis' last 5 games on the road.
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Our St. Louis Cardinals vs Pittsburgh Pirates Prediction
Get ready for a high-scoring finale on Wednesday as Cardinals RHP Erick Fedde starts against Pirates RHP Mitch Keller. The total has gone OVER in the first two games, and I expect the trend to continue since both starters are coming off disastrous stints on the mound. Keller allowed seven runs over 3.2 innings in a 4-9 loss to the Yankees, while Fedde surrendered six runs over 3.0 innings in a 9-13 loss to the Boston Red Sox. The total has gone OVER in 4 of St. Louis' last 5 games on the road and 5 of Pittsburgh's last 5 games. Our betting prediction for Pittsburgh Pirates vs. St. Louis Cardinals: Over 7.5 Runs.
All tips are fully researched and given in good faith, but profits cannot be guaranteed.

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