Pittsburgh Pirates vs St. Louis Cardinals Prediction & Picks - MLB

USA - MLB

Pittsburgh Pirates
5/7/25 13:15
St. Louis Cardinals

Prediction:

 

Over 7.5

-109
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 by Carlos Zabala in MLB Picks

Skenes pitching for the Pirates no longer guarantees any guaranteed advantage, either in betting or in the development of baseball games, for the Pittsburgh team, not because of poor starts by the sensational rookie pitcher but because of the lackluster offensive support he receives. Skenes threw five scoreless bats in the first five innings, but up to that point the game was tied 0-0. The Cardinals' Burleson hit a two-run double off Skenes, which at that point made it 1-2 in favor of the Cards, and that was the final score.

Hayes remains the Pirates' only hot hitter. He was the one who broke the five-inning no-hit streak that Cardinals pitcher Liberatore had in Game 2.

With this, the Cardinals will be looking to sweep the Pirates at Busch Stadium, seeking to extend their winning streak to four consecutive games. Betting action suggests this is very likely to happen in Game 3, with the Cards as heavy favorites at -175 odds.

Pittsburgh Pirates vs St. Louis Cardinals Form

Table

Teams % P W L
14
St. Louis Cardinals
St. Louis Cardinals
0.5 38 19 19
28
Pittsburgh Pirates
Pittsburgh Pirates
0.316 38 12 26

Pittsburgh Pirates and St. Louis Cardinals Latest Matches

Pittsburgh Pirates
Pittsburgh Pirates Latest matches
L L L L L L
Victories

0/6 (0%)

Defeats

6/6 (100%)

May 6, 2025 - MLB

Pittsburgh Pirates
1 :  2
St. Louis Cardinals

May 5, 2025 - MLB

Pittsburgh Pirates
3 :  6
St. Louis Cardinals

May 4, 2025 - MLB

San Diego Padres
4 :  0
Pittsburgh Pirates

May 3, 2025 - MLB

San Diego Padres
2 :  1
Pittsburgh Pirates

May 2, 2025 - MLB

San Diego Padres
9 :  4
Pittsburgh Pirates

May 1, 2025 - MLB

Chicago Cubs
8 :  3
Pittsburgh Pirates
L W L L L L
Victories

1/6 (17%)

Defeats

5/6 (83%)

May 4, 2025 - MLB

San Diego Padres
4 :  0
Pittsburgh Pirates

May 3, 2025 - MLB

San Diego Padres
2 :  1
Pittsburgh Pirates

May 2, 2025 - MLB

San Diego Padres
9 :  4
Pittsburgh Pirates

May 1, 2025 - MLB

Chicago Cubs
8 :  3
Pittsburgh Pirates

Apr 30, 2025 - MLB

Chicago Cubs
3 :  4
Pittsburgh Pirates

Apr 29, 2025 - MLB

Chicago Cubs
9 :  0
Pittsburgh Pirates
L W L L L L
Victories

1/6 (17%)

Defeats

5/6 (83%)

May 6, 2025 - MLB

Pittsburgh Pirates
1 :  2
St. Louis Cardinals

May 5, 2025 - MLB

Pittsburgh Pirates
3 :  6
St. Louis Cardinals

Apr 27, 2025 - MLB

Pittsburgh Pirates
2 :  9
Los Angeles Dodgers

Apr 26, 2025 - MLB

Pittsburgh Pirates
4 :  8
Los Angeles Dodgers

Apr 25, 2025 - MLB

Pittsburgh Pirates
3 :  0
Los Angeles Dodgers

Apr 24, 2025 - MLB

Pittsburgh Pirates
3 :  4
Los Angeles Angels
St. Louis Cardinals
St. Louis Cardinals Latest matches
L L W W W W
Victories

4/6 (67%)

Defeats

2/6 (33%)

May 6, 2025 - MLB

Pittsburgh Pirates
1 :  2
St. Louis Cardinals

May 5, 2025 - MLB

Pittsburgh Pirates
3 :  6
St. Louis Cardinals

May 4, 2025 - MLB

New York Mets
4 :  5
St. Louis Cardinals

May 4, 2025 - MLB

New York Mets
5 :  6
St. Louis Cardinals

May 2, 2025 - MLB

New York Mets
9 :  3
St. Louis Cardinals

May 1, 2025 - MLB

St. Louis Cardinals
1 :  9
Cincinnati Reds
L L W W W W
Victories

4/6 (67%)

Defeats

2/6 (33%)

May 6, 2025 - MLB

Pittsburgh Pirates
1 :  2
St. Louis Cardinals

May 5, 2025 - MLB

Pittsburgh Pirates
3 :  6
St. Louis Cardinals

May 4, 2025 - MLB

New York Mets
4 :  5
St. Louis Cardinals

May 4, 2025 - MLB

New York Mets
5 :  6
St. Louis Cardinals

May 2, 2025 - MLB

New York Mets
9 :  3
St. Louis Cardinals

Apr 27, 2025 - MLB

Milwaukee Brewers
7 :  1
St. Louis Cardinals
W L L W W L
Victories

3/6 (50%)

Defeats

3/6 (50%)

May 1, 2025 - MLB

St. Louis Cardinals
1 :  9
Cincinnati Reds

Apr 30, 2025 - MLB

St. Louis Cardinals
9 :  1
Cincinnati Reds

Apr 30, 2025 - MLB

St. Louis Cardinals
6 :  0
Cincinnati Reds

Apr 28, 2025 - MLB

St. Louis Cardinals
1 :  3
Cincinnati Reds

Apr 23, 2025 - MLB

St. Louis Cardinals
1 :  4
Atlanta Braves

Apr 22, 2025 - MLB

St. Louis Cardinals
10 :  4
Atlanta Braves

Pittsburgh Pirates against St. Louis Cardinals : Head to Head (H2H)

Pittsburgh Pirates

50 %

St. Louis Cardinals

50 %

May 6, 2025 - MLB

Pittsburgh Pirates
1 :  2
St. Louis Cardinals

May 5, 2025 - MLB

Pittsburgh Pirates
3 :  6
St. Louis Cardinals

Apr 9, 2025 - MLB

St. Louis Cardinals
1 :  2
Pittsburgh Pirates

Apr 8, 2025 - MLB

St. Louis Cardinals
5 :  3
Pittsburgh Pirates

Apr 7, 2025 - MLB

St. Louis Cardinals
4 :  8
Pittsburgh Pirates

Sep 19, 2024 - MLB

Pittsburgh Pirates
3 :  2
St. Louis Cardinals

Pittsburgh Pirates - St. Louis Cardinals Key Points

  1. The last two times Keller pitched against the Cardinals, they won 2-1
  2. The Cardinals' 258 overall AVG this season
  3. The Pirates' 4-7 record in Game 3 series this season
  4. Keller and Gray both allowed a home run in their last starts

Our Pittsburgh Pirates vs St. Louis Cardinals Prediction

Liberatore pitched a great game, while it was abundantly clear that Tuesday's game would be low-scoring with Skenes. That may not be the case Wednesday, as Keller of the Pirates and Gray of the Cardinals are well-known starters for the opposing team. The Cardinals' bats, especially Contreras's, have had a strong start to May. Expect more than 7.5 runs in Game 3 on Wednesday. Our prediction for Cardinals vs Pirates is: Over 7.5 runs.

Prediction:

 

Over 7.5

-109
$200 offered for betting!

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Pittsburgh Pirates vs St. Louis Cardinals Picks