Minnesota Twins vs Los Angeles Dodgers Prediction & Picks - MLB

USA - MLB

Minnesota Twins
7/21/25 22:10
Los Angeles Dodgers

Prediction:

 

Over 8.5

-124
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 by Erik Gibbs in MLB Picks

The Minnesota Twins and Los Angeles Dodgers kick off a compelling three-game interleague series today at Dodger Stadium. Both clubs are looking to shift momentum following mixed starts to the second half of the season. While the Twins narrowly avoided a sweep by winning the final game of their last series, the Dodgers are reeling from a series sweep and have struggled with just two victories in their last 12 outings.

The recent head-to-head history between these two franchises heavily favors Los Angeles. The Dodgers have dominated the matchup, winning 14 of the last 16 meetings against Minnesota. In their 2024 series, the Dodgers took two out of three games at Target Field, showcasing their lineup depth and superior pitching. Now back home, the Dodgers hope to reassert themselves after a disappointing post-All-Star break stretch.

Despite recent struggles, Los Angeles still holds the top spot in the NL West and boasts one of the most dangerous lineups in baseball. Shohei Ohtani continues to shine in his first season with the Dodgers, leading the team with 105 hits and 65 RBI. Alongside him, Andy Pages and Freddie Freeman have formed a formidable trio, combining for nearly 200 hits and over 100 RBI. Offensively, the Dodgers remain a threat every night, but their pitching woes have started to overshadow their potent bats.

Minnesota Twins vs Los Angeles Dodgers Form

Table

Teams % P W L
5
Los Angeles Dodgers
Los Angeles Dodgers
0.58 100 58 42
21
Minnesota Twins
Minnesota Twins
0.485 99 48 51

Minnesota Twins and Los Angeles Dodgers Latest Matches

Minnesota Twins
Minnesota Twins Latest matches
W W L L L W
Victories

3/6 (50%)

Defeats

3/6 (50%)

Jul 20, 2025 - MLB

Minnesota Twins
7 :  1
Colorado Rockies

Jul 19, 2025 - MLB

Minnesota Twins
6 :  10
Colorado Rockies

Jul 18, 2025 - MLB

Minnesota Twins
4 :  6
Colorado Rockies

Jul 13, 2025 - MLB

Pittsburgh Pirates
2 :  1
Minnesota Twins

Jul 12, 2025 - MLB

Pittsburgh Pirates
4 :  12
Minnesota Twins

Jul 11, 2025 - MLB

Pittsburgh Pirates
1 :  2
Minnesota Twins
W W L W W L
Victories

4/6 (67%)

Defeats

2/6 (33%)

Jul 13, 2025 - MLB

Pittsburgh Pirates
2 :  1
Minnesota Twins

Jul 12, 2025 - MLB

Pittsburgh Pirates
4 :  12
Minnesota Twins

Jul 11, 2025 - MLB

Pittsburgh Pirates
1 :  2
Minnesota Twins

Jul 10, 2025 - MLB

Chicago Cubs
8 :  1
Minnesota Twins

Jul 9, 2025 - MLB

Chicago Cubs
2 :  4
Minnesota Twins

Jul 8, 2025 - MLB

Chicago Cubs
1 :  8
Minnesota Twins
L W L L L W
Victories

2/6 (33%)

Defeats

4/6 (67%)

Jul 20, 2025 - MLB

Minnesota Twins
7 :  1
Colorado Rockies

Jul 19, 2025 - MLB

Minnesota Twins
6 :  10
Colorado Rockies

Jul 18, 2025 - MLB

Minnesota Twins
4 :  6
Colorado Rockies

Jul 3, 2025 - MLB

Minnesota Twins
1 :  4
Miami Marlins

Jul 2, 2025 - MLB

Minnesota Twins
2 :  1
Miami Marlins

Jul 1, 2025 - MLB

Minnesota Twins
0 :  2
Miami Marlins
Los Angeles Dodgers
Los Angeles Dodgers Latest matches
L W W L L L
Victories

2/6 (33%)

Defeats

4/6 (67%)

Jul 20, 2025 - MLB

Milwaukee Brewers
6 :  5
Los Angeles Dodgers

Jul 19, 2025 - MLB

Milwaukee Brewers
8 :  7
Los Angeles Dodgers

Jul 18, 2025 - MLB

Milwaukee Brewers
2 :  0
Los Angeles Dodgers

Jul 13, 2025 - MLB

Los Angeles Dodgers
5 :  2
San Francisco Giants

Jul 12, 2025 - MLB

Los Angeles Dodgers
2 :  1
San Francisco Giants

Jul 11, 2025 - MLB

Los Angeles Dodgers
7 :  8
San Francisco Giants
L L L L L L
Victories

0/6 (0%)

Defeats

6/6 (100%)

Jul 20, 2025 - MLB

Milwaukee Brewers
6 :  5
Los Angeles Dodgers

Jul 19, 2025 - MLB

Milwaukee Brewers
8 :  7
Los Angeles Dodgers

Jul 18, 2025 - MLB

Milwaukee Brewers
2 :  0
Los Angeles Dodgers

Jul 6, 2025 - MLB

Houston Astros
5 :  1
Los Angeles Dodgers

Jul 5, 2025 - MLB

Houston Astros
6 :  4
Los Angeles Dodgers

Jul 4, 2025 - MLB

Houston Astros
18 :  1
Los Angeles Dodgers
L L L W L W
Victories

2/6 (33%)

Defeats

4/6 (67%)

Jul 13, 2025 - MLB

Los Angeles Dodgers
5 :  2
San Francisco Giants

Jul 12, 2025 - MLB

Los Angeles Dodgers
2 :  1
San Francisco Giants

Jul 11, 2025 - MLB

Los Angeles Dodgers
7 :  8
San Francisco Giants

Jul 9, 2025 - MLB

Los Angeles Dodgers
2 :  3
Milwaukee Brewers

Jul 8, 2025 - MLB

Los Angeles Dodgers
1 :  3
Milwaukee Brewers

Jul 7, 2025 - MLB

Los Angeles Dodgers
1 :  9
Milwaukee Brewers

Minnesota Twins against Los Angeles Dodgers : Head to Head (H2H)

Minnesota Twins

50 %

Los Angeles Dodgers

50 %

Apr 10, 2024 - MLB

Los Angeles Dodgers
2 :  3
Minnesota Twins

Apr 8, 2024 - MLB

Los Angeles Dodgers
4 :  2
Minnesota Twins

Minnesota Twins - Los Angeles Dodgers Key Points

  1. The Dodgers are 12-0 in their last 12 night games vs. AL Central teams with a losing record
  2. The Twins are 0-4 in their last 4 games vs. the Dodgers after a win
  3. The Dodgers are 6-0 covering the run line in their last 6 Monday games vs. AL teams
  4. The Twins are 1-6 covering the run line in their last 8 away games

Our Minnesota Twins vs Los Angeles Dodgers Prediction

Ohtani is slated to make another start on the mound today, and while he may not go deep into the game, his presence brings stability to a shaky rotation. He’s given up just one run across nine innings in his last appearances, signaling growing confidence and rhythm as a pitcher. Once Ohtani exits, Dustin May is expected to take the ball. May had a rough outing in his last start but has the tools to rebound, especially against a Minnesota team that has struggled to generate consistent offense.

The Twins will counter with David Festa, a young arm who has been inconsistent in his recent turns. The Dodgers’ stacked lineup will likely test him early, and unless he finds command quickly, he could be in for a long night. Minnesota has played tough in spurts, but their track record against L.A. doesn’t inspire much optimism.

With their backs against the wall and playing at home, the Dodgers are primed to bounce back. Their talent level is too high to stay down for long, and this matchup provides a perfect opportunity to reset the tone for the second half of the season. Our prediction for LA Dodgers vs. Minnesota Twins: Dodgers to win.

Prediction:

 

Over 8.5

-124
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Minnesota Twins vs Los Angeles Dodgers Picks