Manchester City vs Napoli Prediction & Picks - Champions League

Europe - Champions League

Manchester City
9/18/25 15:00
Napoli

Prediction:

 

Napoli to win (Draw no bet)

+255
$300 offered for betting!

New customers only | Commercial content | 21+ age limit | T&Cs apply

 by Simon Day in Champions League Picks

Thursday's Champions League action is highlighted by a blockbuster clash between Manchester City and Serie A champions Napoli. City have had an up-and-down start to the new season, but Sunday's resounding 3-0 success over Manchester City will have given them a huge confidence boost. Erling Haaland was the star of the show in that derby day victory, with two goals and an outstanding all round display, but City boss Pep Guardiola will also have been delighted by his side's overall performance following two disappointing defeats. 

City will need to be at their best again on Thursday, as they face an in-form Napoli side that have started the Serie A season with three consecutive victories. Their latest success came courtesy of a comfortable 1-3 win at Fiorentina, with new signing Rasmus Højlund marking his debut with a well-taken goal. With the likes of Kevin De Bruyne, Scott McTominay and Frank Anguissa also in excellent form, Napoli will be confident of mounting a serious challenge for Champions League glory. 

Up to $300 to bet on Manchester City - Napoli! 

Limited Offer. Currently at FanDuel

Manchester City vs Napoli Form

Table

Teams Pts P W D L GD
8
Napoli
Napoli
0 0 0 0 0 0
8
Manchester City
Manchester City
0 0 0 0 0 0

Manchester City and Napoli Latest Matches

Manchester City
Manchester City Latest matches
L W W L L W
Victories

3/6 (50%)

Draw

0/6 (0%)

Defeats

3/6 (50%)

Average stats (Last 6 matchs)

3.67 Total goals
33% BTTS
2.33 Goals scored
1.33 Goals conceded
83% Over 2.5
17% Under 2.5

Sep 14, 2025 - Premier League

Manchester City
3 :  0
Manchester United

Aug 31, 2025 - Premier League

Brighton
2 :  1
Manchester City

Aug 23, 2025 - Premier League

Manchester City
0 :  2
Tottenham

Aug 16, 2025 - Premier League

Wolves
0 :  4
Manchester City

Aug 9, 2025 - Clubs Friendlies

Palermo
0 :  3
Manchester City

Jun 30, 2025 - Club World Cup

Manchester City
3 :  4
Al Hilal
W W W L L W
Victories

4/6 (67%)

Draw

0/6 (0%)

Defeats

2/6 (33%)

Average stats (Last 6 matchs)

4 Total goals
33% BTTS
2.83 Goals scored
1.17 Goals conceded
67% Over 2.5
33% Under 2.5

Sep 14, 2025 - Premier League

Manchester City
3 :  0
Manchester United

Aug 23, 2025 - Premier League

Manchester City
0 :  2
Tottenham

Jun 30, 2025 - Club World Cup

Manchester City
3 :  4
Al Hilal

Jun 22, 2025 - Club World Cup

Manchester City
6 :  0
Al Ain FC

Jun 18, 2025 - Club World Cup

Manchester City
2 :  0
WAC Casablanca

May 20, 2025 - Premier League

Manchester City
3 :  1
Bournemouth
L W W W W L
Victories

4/6 (67%)

Draw

0/6 (0%)

Defeats

2/6 (33%)

Average stats (Last 6 matchs)

3.33 Total goals
33% BTTS
2.5 Goals scored
0.83 Goals conceded
67% Over 2.5
33% Under 2.5

Aug 31, 2025 - Premier League

Brighton
2 :  1
Manchester City

Aug 16, 2025 - Premier League

Wolves
0 :  4
Manchester City

Aug 9, 2025 - Clubs Friendlies

Palermo
0 :  3
Manchester City

Jun 26, 2025 - Club World Cup

Juventus
2 :  5
Manchester City

May 25, 2025 - Premier League

Fulham
0 :  2
Manchester City

May 17, 2025 - FA Cup

Crystal Palace
1 :  0
Manchester City
Napoli
Napoli Latest matches
W W W W W W
Victories

6/6 (100%)

Draw

0/6 (0%)

Defeats

0/6 (0%)

Average stats (Last 6 matchs)

3.17 Total goals
50% BTTS
2.5 Goals scored
0.67 Goals conceded
67% Over 2.5
33% Under 2.5

Sep 13, 2025 - Serie A

Fiorentina
1 :  3
Napoli

Aug 30, 2025 - Serie A

Napoli
1 :  0
Cagliari

Aug 23, 2025 - Serie A

Sassuolo
0 :  2
Napoli

Aug 14, 2025 - Clubs Friendlies

Napoli
2 :  1
Olympiacos

Aug 10, 2025 - Clubs Friendlies

Napoli
4 :  0
ASD Sorrento 1945

Aug 9, 2025 - Clubs Friendlies

Napoli
3 :  2
Girona
L D W W W W
Victories

4/6 (67%)

Draw

1/6 (17%)

Defeats

1/6 (17%)

Average stats (Last 6 matchs)

3 Total goals
67% BTTS
2 Goals scored
1 Goals conceded
67% Over 2.5
33% Under 2.5

Aug 30, 2025 - Serie A

Napoli
1 :  0
Cagliari

Aug 14, 2025 - Clubs Friendlies

Napoli
2 :  1
Olympiacos

Aug 10, 2025 - Clubs Friendlies

Napoli
4 :  0
ASD Sorrento 1945

Aug 9, 2025 - Clubs Friendlies

Napoli
3 :  2
Girona

Aug 4, 2025 - Clubs Friendlies

Napoli
1 :  1
Casertana

Aug 3, 2025 - Clubs Friendlies

Napoli
1 :  2
Brest
D W W D W W
Victories

4/6 (67%)

Draw

2/6 (33%)

Defeats

0/6 (0%)

Average stats (Last 6 matchs)

1.67 Total goals
33% BTTS
1.33 Goals scored
0.33 Goals conceded
17% Over 2.5
83% Under 2.5

Sep 13, 2025 - Serie A

Fiorentina
1 :  3
Napoli

Aug 23, 2025 - Serie A

Sassuolo
0 :  2
Napoli

May 18, 2025 - Serie A

Parma
0 :  0
Napoli

May 3, 2025 - Serie A

Lecce
0 :  1
Napoli

Apr 19, 2025 - Serie A

Monza
0 :  1
Napoli

Apr 7, 2025 - Serie A

Bologna
1 :  1
Napoli

Manchester City against Napoli : Head to Head (H2H)

Manchester City

100 %

Draw

0 %

Napoli

0 %

Average stats (last H2H results)

4.5
Total goals
100%
BTTS
3
Goals scored (Team 1)
1.5
Goals scored (Team 2)
100%
Over 2.5
0%
Under 2.5

Nov 1, 2017 - Champions League

Napoli
2 :  4
Manchester City

Oct 17, 2017 - Champions League

Manchester City
2 :  1
Napoli

Napoli v Manchester City last Lineups

Manchester City

Formation : 4 - 3 - 3

25
G. Donnarumma
33
N. O'Reilly
45
A. Khusanov
3
R. Dias
24
J. Gvardiol
20
B. Silva
16
Rodri
4
T. Reijnders
47
P. Foden
9
E. Haaland
11
J. Doku
19
R. Hojlund
8
S. Mctominay
99
F. Anguissa
11
K. De Bruyne
21
M. Politano
68
S. Lobotka
37
L. Spinazzola
4
A. Buongiorno
31
S. Beukema
22
G. Di Lorenzo
32
V. Milinkovic-Savic

Formation : 4 - 1 - 4 - 1

Napoli

Missing players

Manchester City
Manchester City
Defender

R. Ait Nouri

J. Stones

Midfielder

M. Kovacic

R. Cherki

Forward

O. Marmoush

Napoli
Napoli
Goalkeeper

N. Contini

Defender

A. Rrahmani

Forward

R. Lukaku

Most goals and assists

CD Huachipato Manchester City
CD Huachipato Napoli
Top Goalscorer
Norway E. Haaland (5 Goals)
Top Goalscorer
Belgium K. De Bruyne (2 Goals)
Best assists
Belgium J. Doku (2 Assists)
Best assists
Italy M. Politano (1 Assists)
Italy A. Buongiorno (1 Assists)
Italy L. Spinazzola (1 Assists)
Cameroon F. Anguissa (1 Assists)

Manchester City - Napoli Key Points

  1. Napoli have not lost since February 23rd
  2. Man City have 2 wins and 3 defeats from their last 5 matches
  3. Napoli have won all 3 of their Serie A matches this season
  4. Man City have won just 1 of their last 7 Champions League games
Up to $300 to bet on Manchester City - Napoli! 

Limited Offer. Currently at FanDuel

Our Manchester City vs Napoli Prediction

City are very strong favorites here, but Napoli are rapidly turning into one of the most feared teams in Europe, so we think there is solid value in betting against the home side. Antonio Conte has made his Napoli team extremely tough to beat, so whilst City were much improved in their victory over United, we think this will be a much tougher test for Pep Guardiola's side. Napoli are 4.20 for the win, but we are hedging our bets slightly by taking the 3.55 on an away win with 'draw no bet'. Our prediction for Manchester City vs Napoli is: Napoli to win (Draw no bet).

Prediction:

 

Napoli to win (Draw no bet)

+255
$300 offered for betting!

Grab an extra $300 for your Manchester City vs Napoli wager!

Bet $5, Get $300

Get ready to experience the thrill of the game with FanDuel's exciting welcome offer, available for use on the Manchester City vs Napoli matchup!

A minimum bet of $5 will qualify for $300 in bonus bets if your bet wins! This offer is a golden opportunity for new users. Don't miss out on this limited-time deal to enhance your sports betting experience with some extra oomph! Jump into the action today and let FanDuel take your sports engagement to the next level!

$300 available for Manchester City vs Napoli

All tips are fully researched and given in good faith, but profits cannot be guaranteed.

Manchester City vs Napoli Picks
Up to $300 to bet on Manchester City - Napoli! 

Limited Offer. Currently at FanDuel