Los Angeles Dodgers vs Baltimore Orioles Prediction & Picks - MLB

Prediction published on 9/5/25, 3:41 PM  by Lou Aguila in MLB Picks

On Friday, the Los Angeles Dodgers open a fresh series against the Baltimore Orioles after being on the receiving end of a devastating sweep at the hands of the Pittsburgh Pirates.

The Dodgers are still the favorites at -165, though bettors should take a closer look at their scheduled starter for Game 1, Tyler Glasnow, who is 1-4 with a 3.45 ERA across his last five starts.

Current Form:

The Dodgers are 1-4 in their last five games, having lost their last three games to the Pittsburgh Pirates. At 78-62, the Dodgers are hanging on to a 2-2-game lead on the San Diego Padres, who carry a 76-64 record. In this five-game stretch, the Dodgers have struggled mightily on offense and defense, averaging 3.3 runs per game on a .244 batting average and pitching a 5.79 ERA. The Dodgers are still missing the service of Max Muncy, who is nursing an oblique injury. Will Smith will likely miss the series opener against the Orioles because of a hand injury.

The Orioles have won four of their last five games, including a three-game sweep of the Padres, to improve their record to 64-76. Mathematically, Baltimore still has a small window to make one final push towards securing a wild card nod in the American League, as they are only 9 games separating them and the Seattle Mariners, who sport a 74-66 record and hold the third and final wild card in the American League. However, the Orioles understand that they would have to improve their numbers across the board to pull off that miracle run. Over the last five games, the Orioles have averaged 6.0 runs per game on a .286 batting average while maintaining a 4.09 ERA.