Kansas City Royals vs Chicago Cubs Prediction & Picks - MLB

USA - MLB

Kansas City Royals
7/22/25 20:05
Chicago Cubs

Prediction:

 

Cubs -1.5

-110
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 by Travis Pulver in MLB Picks

The Chicago Cubs will host the Kansas City Royals today in Game Two of a three-game series at Wrigley Field in the Windy City. Fans can follow the contest once it begins at 8:05 p.m. EST. Game One of the series went to the Royals yesterday, 12-4. Chicago got ahead 4-1 after the second but failed to score again. Kansas City tacked on two in the top of the fourth and then took the lead for good with four in the fifth. A four-run eighth for the Royals closed out the scoring.

 A former Cubbie, Rich Hill, is scheduled to start the game for Kansas City. The 45-year-old has been pitching for the Royals Triple-A team since the beginning of June. In 42 innings, he has posted a 5.36 ERA and a 1.62 WHIP. He’ll become the oldest player in the league once the Royals call him up. While he is slated to be the starter, there is talk that he could be used in bulk relief, so it is unclear how long his leash may be. As for the Cubs, they’ll hand the ball to Matthew Boyd to start the day. Boyd is 10-3 in 19 starts with a 2.34 ERA, 1.03 WHIP, and .227 OBA. He has gone 8-0 In nine home starts, with a 2.21 ERA and .207 OBA.

Kansas City Royals vs Chicago Cubs Form

Table

Teams % P W L
1
Chicago Cubs
Chicago Cubs
0.594 101 60 41
22
Kansas City Royals
Kansas City Royals
0.48 102 49 53

Kansas City Royals and Chicago Cubs Latest Matches

Kansas City Royals
Kansas City Royals Latest matches
L W L L W W
Victories

3/6 (50%)

Defeats

3/6 (50%)

Jul 21, 2025 - MLB

Kansas City Royals
12 :  4
Chicago Cubs

Jul 20, 2025 - MLB

Kansas City Royals
7 :  4
Miami Marlins

Jul 19, 2025 - MLB

Kansas City Royals
1 :  3
Miami Marlins

Jul 18, 2025 - MLB

Kansas City Royals
7 :  8
Miami Marlins

Jul 13, 2025 - MLB

New York Mets
2 :  3
Kansas City Royals

Jul 12, 2025 - MLB

New York Mets
3 :  1
Kansas City Royals
W W W L L W
Victories

4/6 (67%)

Defeats

2/6 (33%)

Jul 13, 2025 - MLB

New York Mets
2 :  3
Kansas City Royals

Jul 12, 2025 - MLB

New York Mets
3 :  1
Kansas City Royals

Jul 11, 2025 - MLB

New York Mets
8 :  3
Kansas City Royals

Jul 9, 2025 - MLB

Pittsburgh Pirates
3 :  4
Kansas City Royals

Jul 8, 2025 - MLB

Pittsburgh Pirates
3 :  4
Kansas City Royals

Jul 7, 2025 - MLB

Pittsburgh Pirates
3 :  9
Kansas City Royals
L W L L W W
Victories

3/6 (50%)

Defeats

3/6 (50%)

Jul 21, 2025 - MLB

Kansas City Royals
12 :  4
Chicago Cubs

Jul 20, 2025 - MLB

Kansas City Royals
7 :  4
Miami Marlins

Jul 19, 2025 - MLB

Kansas City Royals
1 :  3
Miami Marlins

Jul 18, 2025 - MLB

Kansas City Royals
7 :  8
Miami Marlins

Jul 6, 2025 - MLB

Kansas City Royals
4 :  0
Arizona Diamondbacks

Jul 5, 2025 - MLB

Kansas City Royals
1 :  7
Arizona Diamondbacks
Chicago Cubs
Chicago Cubs Latest matches
W W W W L L
Victories

4/6 (67%)

Defeats

2/6 (33%)

Jul 21, 2025 - MLB

Kansas City Royals
12 :  4
Chicago Cubs

Jul 20, 2025 - MLB

Boston Red Sox
6 :  1
Chicago Cubs

Jul 19, 2025 - MLB

Boston Red Sox
0 :  6
Chicago Cubs

Jul 18, 2025 - MLB

Boston Red Sox
1 :  4
Chicago Cubs

Jul 13, 2025 - MLB

Chicago Cubs
4 :  1
New York Yankees

Jul 12, 2025 - MLB

Chicago Cubs
5 :  2
New York Yankees
L W W W L L
Victories

3/6 (50%)

Defeats

3/6 (50%)

Jul 21, 2025 - MLB

Kansas City Royals
12 :  4
Chicago Cubs

Jul 20, 2025 - MLB

Boston Red Sox
6 :  1
Chicago Cubs

Jul 19, 2025 - MLB

Boston Red Sox
0 :  6
Chicago Cubs

Jul 18, 2025 - MLB

Boston Red Sox
1 :  4
Chicago Cubs

Jul 6, 2025 - MLB

St. Louis Cardinals
0 :  11
Chicago Cubs

Jul 5, 2025 - MLB

St. Louis Cardinals
8 :  6
Chicago Cubs
L L W L W W
Victories

3/6 (50%)

Defeats

3/6 (50%)

Jul 13, 2025 - MLB

Chicago Cubs
4 :  1
New York Yankees

Jul 12, 2025 - MLB

Chicago Cubs
5 :  2
New York Yankees

Jul 11, 2025 - MLB

Chicago Cubs
0 :  11
New York Yankees

Jul 10, 2025 - MLB

Chicago Cubs
8 :  1
Minnesota Twins

Jul 9, 2025 - MLB

Chicago Cubs
2 :  4
Minnesota Twins

Jul 8, 2025 - MLB

Chicago Cubs
1 :  8
Minnesota Twins

Kansas City Royals against Chicago Cubs : Head to Head (H2H)

Kansas City Royals

50 %

Chicago Cubs

50 %

Jul 21, 2025 - MLB

Kansas City Royals
12 :  4
Chicago Cubs

Mar 6, 2025 - MLB Spring Training

Kansas City Royals
9 :  3
Chicago Cubs

Mar 1, 2025 - MLB Spring Training

Chicago Cubs
11 :  1
Kansas City Royals

Jul 28, 2024 - MLB

Chicago Cubs
7 :  3
Kansas City Royals

Jul 27, 2024 - MLB

Chicago Cubs
9 :  4
Kansas City Royals

Jul 26, 2024 - MLB

Chicago Cubs
0 :  6
Kansas City Royals

Kansas City Royals - Chicago Cubs Key Points

  1. Chicago leads the all-time series vs. Kansas City 21-17 with a 12-9 record at home.
  2. The Cubs are 30-13 when favored at home.
  3. The Royals are 21-21 when an underdog on the road.
  4. Betting Public: 89% of runline tickets and the handle are on the Cubs.

Our Kansas City Royals vs Chicago Cubs Prediction

Chicago hasn’t been hitting the ball poorly of late (.258 since the All-Star Break); they just aren’t generating many runs (15 in four games; Royals scored 27). Kansas City’s bats came alive yesterday, but don’t count on that happening today vs. Boyd. Instead, look for the Cubs lineup to beat up on Hill and get out to a big early lead.

Kansas City vs. Chicago Pick: Cubs -1.5

Prediction:

 

Cubs -1.5

-110
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Kansas City Royals vs Chicago Cubs Picks