Philadelphia Eagles vs Los Angeles Chargers Prediction & Picks - NFL

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Philadelphia Eagles
12/8/25 20:15
Los Angeles Chargers

Prediction:

 

LA Chargers ML

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 by Travis Pulver in NFL Picks

The Philadelphia Eagles will try to get back on the right side of the scoreboard this week when they head out to the West Coast to take on the Los Angeles Chargers on Monday Night Football. Gametime at SoFi Stadium in Inglewood, CA, is scheduled for 8:15 p.m. EST.

Philadelphia comes into the game in control of the NFC East, but losers of their last two games (vs. the Cowboys and Bears). After getting out to a 21-point lead early in the second quarter vs. the Cowboys, they were outscored 24-0 the rest of the way. Against the Bears, the offense never really got on track as the Chicago offense dictated the pace of the game; a late fourth-quarter touchdown made the final score look closer than the game really was. As for the Chargers, they’ve had some issues in recent weeks, but the big concern this week is the health of QB Justin Herbert, who recently had surgery on his non-throwing hand. He has been limited in practice this week and is considered questionable for Monday’s game. If he doesn’t go, Trey Lance would get the start, which would undoubtedly lead to a run-heavy approach for the game against an Eagles defense that will be down one of its best players in Jalen Carter.

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Philadelphia Eagles vs Los Angeles Chargers Form

Table

Teams % P W D L
8
Philadelphia Eagles
Philadelphia Eagles
0.667 12 8 0 4
11
Los Angeles Chargers
Los Angeles Chargers
0.667 12 8 0 4

Philadelphia Eagles and Los Angeles Chargers Latest Matches

Philadelphia Eagles
Philadelphia Eagles Latest matches
W W W W L L
Victories

4/6 (67%)

Draw

0/6 (0%)

Defeats

2/6 (33%)

Nov 28, 2025 - NFL

Chicago Bears
24 :  15
Philadelphia Eagles

Nov 23, 2025 - NFL

Philadelphia Eagles
21 :  24
Dallas Cowboys

Nov 16, 2025 - NFL

Detroit Lions
9 :  16
Philadelphia Eagles

Nov 10, 2025 - NFL

Philadelphia Eagles
10 :  7
Green Bay Packers

Oct 26, 2025 - NFL

New York Giants
20 :  38
Philadelphia Eagles

Oct 19, 2025 - NFL

Philadelphia Eagles
28 :  22
Minnesota Vikings
W W L W W L
Victories

4/6 (67%)

Draw

0/6 (0%)

Defeats

2/6 (33%)

Nov 28, 2025 - NFL

Chicago Bears
24 :  15
Philadelphia Eagles

Nov 16, 2025 - NFL

Detroit Lions
9 :  16
Philadelphia Eagles

Oct 26, 2025 - NFL

New York Giants
20 :  38
Philadelphia Eagles

Oct 5, 2025 - NFL

Denver Broncos
21 :  17
Philadelphia Eagles

Sep 21, 2025 - NFL

Los Angeles Rams
26 :  33
Philadelphia Eagles

Sep 4, 2025 - NFL

Dallas Cowboys
20 :  24
Philadelphia Eagles
W W L W W L
Victories

4/6 (67%)

Draw

0/6 (0%)

Defeats

2/6 (33%)

Nov 23, 2025 - NFL

Philadelphia Eagles
21 :  24
Dallas Cowboys

Nov 10, 2025 - NFL

Philadelphia Eagles
10 :  7
Green Bay Packers

Oct 19, 2025 - NFL

Philadelphia Eagles
28 :  22
Minnesota Vikings

Oct 9, 2025 - NFL

Philadelphia Eagles
17 :  34
New York Giants

Sep 28, 2025 - NFL

Philadelphia Eagles
31 :  25
Tampa Bay Buccaneers

Sep 14, 2025 - NFL

Philadelphia Eagles
20 :  17
Kansas City Chiefs
Los Angeles Chargers
Los Angeles Chargers Latest matches
L W W W L W
Victories

4/6 (67%)

Draw

0/6 (0%)

Defeats

2/6 (33%)

Nov 30, 2025 - NFL

Las Vegas Raiders
14 :  31
Los Angeles Chargers

Nov 16, 2025 - NFL

Los Angeles Chargers
6 :  35
Jacksonville Jaguars

Nov 9, 2025 - NFL

Pittsburgh Steelers
10 :  25
Los Angeles Chargers

Nov 2, 2025 - NFL

Los Angeles Chargers
27 :  20
Tennessee Titans

Oct 23, 2025 - NFL

Minnesota Vikings
10 :  37
Los Angeles Chargers

Oct 19, 2025 - NFL

Indianapolis Colts
38 :  24
Los Angeles Chargers
W L L W W W
Victories

4/6 (67%)

Draw

0/6 (0%)

Defeats

2/6 (33%)

Nov 30, 2025 - NFL

Las Vegas Raiders
14 :  31
Los Angeles Chargers

Nov 9, 2025 - NFL

Pittsburgh Steelers
10 :  25
Los Angeles Chargers

Oct 23, 2025 - NFL

Minnesota Vikings
10 :  37
Los Angeles Chargers

Oct 19, 2025 - NFL

Indianapolis Colts
38 :  24
Los Angeles Chargers

Oct 5, 2025 - NFL

Washington Commanders
27 :  10
Los Angeles Chargers

Sep 21, 2025 - NFL

Denver Broncos
20 :  23
Los Angeles Chargers
L W L W W L
Victories

3/6 (50%)

Draw

0/6 (0%)

Defeats

3/6 (50%)

Nov 16, 2025 - NFL

Los Angeles Chargers
6 :  35
Jacksonville Jaguars

Nov 2, 2025 - NFL

Los Angeles Chargers
27 :  20
Tennessee Titans

Oct 12, 2025 - NFL

Los Angeles Chargers
29 :  27
Miami Dolphins

Sep 28, 2025 - NFL

Los Angeles Chargers
18 :  21
New York Giants

Sep 15, 2025 - NFL

Los Angeles Chargers
20 :  9
Las Vegas Raiders

Jan 11, 2025 - NFL

Los Angeles Chargers
12 :  32
Houston Texans

Philadelphia Eagles - Los Angeles Chargers Key Points

  1. The Chargers lead the all-time series vs. the Eagles 8-5, but the two teams have not played since the 2021 season.
  2. Los Angeles is 5-6-1 ATS this season, while Philadelphia is 7-5.
  3. The OVER is 6-6 for the Chargers and 5-7 for the Eagles.
  4. Betting Public: 19% of moneyline tickets and 11% of the handle are on the Chargers.
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Our Philadelphia Eagles vs Los Angeles Chargers Prediction

Philadelphia’s offense has been a giant question mark all season; they’ve never really established the run, and the passing game has been hit-or-miss. But they’ve managed to stay on the right side of the scoreboard more often than not, thanks to their defense. However, they have not been strong against the run (24th) and will be down Jalen Carter in the interior of the line. Herbert’s health is a concern, but I see the Chargers exploiting the hole Carter’s absence leaves in their run defense while LA’s top-five defense (total yards) keeps the Eagles offense from revving up.

Our Eagles vs. Chargers Pick: LA Chargers ML  

Prediction:

 

LA Chargers ML

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Philadelphia Eagles vs Los Angeles Chargers Picks