USA - NFL
New customers only | Commercial content | 21+ age limit | T&Cs apply
by Matt Lowrimore in NFL Picks
One of the important games on the NFL Week 13 Sunday slate will see the Pittsburgh Steelers take on the Buffalo Bills. Let’s take a look at the match statistics and predictions for this game between the Steelers and the Bills.
Buffalo enters this game with a record of 7-4, having most recently lost to the Houston Texans by a score of 23-19 in Week 12. The Bills’ offense had a total of 326 yards, while its defense allowed 261 yards. Quarterback Josh Allen threw for 253 yards and two interceptions, while running back James Cook III led the team in rushing with 116 yards.
As for Pittsburgh, they enter this game with a record of 6-5, having most recently lost to the Chicago Bears in Week 12 by a score of 31-28. The Steelers’ offense had a total of 345 yards, while its defense allowed 328 yards. Quarterback Mason Rudolph threw for 171 yards, one touchdown, and one interception, while running back Kenneth Gainwell led the team in rushing with 92 yards.
Limited Offer. Currently at DraftKings
Buffalo Bills vs Pittsburgh Steelers Form
Table
| Teams | % | P | W | D | L |
|---|---|---|---|---|---|
|
12
|
0.636 | 11 | 7 | 0 | 4 |
|
15
|
0.545 | 11 | 6 | 0 | 5 |
Buffalo Bills and Pittsburgh Steelers Latest Matches
3/6 (50%)
0/6 (0%)
3/6 (50%)
Nov 20, 2025 - NFL
Nov 16, 2025 - NFL
Nov 9, 2025 - NFL
Nov 2, 2025 - NFL
Oct 26, 2025 - NFL
Oct 13, 2025 - NFL
5/6 (83%)
0/6 (0%)
1/6 (17%)
Nov 16, 2025 - NFL
Nov 2, 2025 - NFL
Oct 5, 2025 - NFL
Sep 28, 2025 - NFL
Sep 18, 2025 - NFL
Sep 7, 2025 - NFL
2/6 (33%)
0/6 (0%)
4/6 (67%)
Nov 20, 2025 - NFL
Nov 9, 2025 - NFL
Oct 26, 2025 - NFL
Oct 13, 2025 - NFL
Sep 14, 2025 - NFL
Jan 26, 2025 - NFL
2/6 (33%)
0/6 (0%)
4/6 (67%)
Nov 23, 2025 - NFL
Nov 16, 2025 - NFL
Nov 9, 2025 - NFL
Nov 2, 2025 - NFL
Oct 26, 2025 - NFL
Oct 16, 2025 - NFL
4/6 (67%)
0/6 (0%)
2/6 (33%)
Nov 16, 2025 - NFL
Nov 2, 2025 - NFL
Oct 26, 2025 - NFL
Oct 12, 2025 - NFL
Sep 28, 2025 - NFL
Sep 14, 2025 - NFL
2/6 (33%)
0/6 (0%)
4/6 (67%)
Nov 23, 2025 - NFL
Nov 9, 2025 - NFL
Oct 16, 2025 - NFL
Sep 21, 2025 - NFL
Sep 7, 2025 - NFL
Jan 11, 2025 - NFL
Buffalo Bills against Pittsburgh Steelers : Head to Head (H2H)
Jan 15, 2024 - NFL
Buffalo Bills - Pittsburgh Steelers Key Points
- The Bills are averaging 28.3 points per game
- The Bills are allowing 22.9 points per game
- The Steelers are averaging 24.9 points per game
- The Steelers are allowing 23.9 points per game
Limited Offer. Currently at DraftKings
Our Buffalo Bills vs Pittsburgh Steelers Prediction
Buffalo is a small favorite in this game, but still looks to be the best betting option. The Bills have struggled at times this season, having lost to Miami and Houston over the last few weeks. However, they still have one of the better rosters in the NFL.
Pittsburgh, on the other hand, is dealing with multiple injuries, including to their quarterback, Aaron Rodgers. His status is still unknown, so if he is unable to play, Mason Rudolph is the likely option to play as a backup.
He has never been a viable option at quarterback; therefore, because the Bills seem to be healthier and overall a better team, our Pittsburgh Steelers vs Buffalo Bills prediction is: Buffalo Bills ML.Claim $200+ for your Buffalo Bills vs Pittsburgh Steelers wager!

Would you like to bet on Buffalo Bills vs Pittsburgh Steelers? For this NFL match, DK treats you to an exclusive offer: a bonus of $200+, no promo code needed! Take advantage while you still can!
Not registered yet? You can create your account now with our link below. A bonus of $200+ awaits you on the Buffalo Bills vs Pittsburgh Steelers match!
All tips are fully researched and given in good faith, but profits cannot be guaranteed.