Arizona Cardinals vs Tampa Bay Buccaneers Prediction & Picks - NFL

USA - NFL

Arizona Cardinals
11/30/25 13:00
Tampa Bay Buccaneers

Prediction:

 

Buccaneers ML

-197
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 by Travis Pulver in NFL Picks

The Tampa Bay Buccaneers will try to end their three-game slide when they host the Arizona Cardinals at Raymond James Stadium in Tampa, FL. Kickoff is scheduled for 1 p.m. EST, and the game will be broadcast on Fox.

A few weeks ago, the Buccaneers appeared to be in complete control of the NFC South, but fast forward three weeks—and three losses – and they are fighting to stay on top with the Carolina Panthers nipping at their heels. This harsh reality may have something to do with Baker Mayfield playing despite leaving the game last week with a shoulder injury. Arizona’s defense is ranked 22nd in the league in sacks with 22; Tampa Bay’s offensive line has given up 24 this season. As for the Cardinals, Arizona‘s passing game has thrived with Jacoby Brissett behind center, averaging over 300 yards a game in the last six. However, with the run game struggling to gain traction (they have not had a 100-yard rusher this season), the passing game has kept them competitive. But despite Brissett’s big numbers, the Cardinals are 1-5 in those games. Why? Because the defense can’t stop anyone (No. 19 in total yards; No. 25 in scoring).

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Arizona Cardinals vs Tampa Bay Buccaneers Form

Table

Teams % P W D L
16
Tampa Bay Buccaneers
Tampa Bay Buccaneers
0.545 11 6 0 5
26
Arizona Cardinals
Arizona Cardinals
0.273 11 3 0 8

Arizona Cardinals and Tampa Bay Buccaneers Latest Matches

Arizona Cardinals
Arizona Cardinals Latest matches
L L W L L L
Victories

1/6 (17%)

Draw

0/6 (0%)

Defeats

5/6 (83%)

Nov 23, 2025 - NFL

Jacksonville Jaguars
27 :  24
Arizona Cardinals

Nov 16, 2025 - NFL

San Francisco 49ers
41 :  22
Arizona Cardinals

Nov 9, 2025 - NFL

Arizona Cardinals
22 :  44
Seattle Seahawks

Nov 3, 2025 - NFL

Arizona Cardinals
27 :  17
Dallas Cowboys

Oct 19, 2025 - NFL

Green Bay Packers
27 :  23
Arizona Cardinals

Oct 12, 2025 - NFL

Arizona Cardinals
27 :  31
Indianapolis Colts
W L L L L L
Victories

1/6 (17%)

Draw

0/6 (0%)

Defeats

5/6 (83%)

Nov 23, 2025 - NFL

Jacksonville Jaguars
27 :  24
Arizona Cardinals

Nov 16, 2025 - NFL

San Francisco 49ers
41 :  22
Arizona Cardinals

Oct 19, 2025 - NFL

Green Bay Packers
27 :  23
Arizona Cardinals

Oct 5, 2025 - NFL

Tennessee Titans
22 :  21
Arizona Cardinals

Sep 25, 2025 - NFL

Seattle Seahawks
23 :  20
Arizona Cardinals

Sep 14, 2025 - NFL

Carolina Panthers
22 :  27
Arizona Cardinals
L W L L W L
Victories

2/6 (33%)

Draw

0/6 (0%)

Defeats

4/6 (67%)

Nov 9, 2025 - NFL

Arizona Cardinals
22 :  44
Seattle Seahawks

Nov 3, 2025 - NFL

Arizona Cardinals
27 :  17
Dallas Cowboys

Oct 12, 2025 - NFL

Arizona Cardinals
27 :  31
Indianapolis Colts

Sep 21, 2025 - NFL

Arizona Cardinals
15 :  16
San Francisco 49ers

Sep 7, 2025 - NFL

Arizona Cardinals
20 :  13
New Orleans Saints

Dec 28, 2024 - NFL

Arizona Cardinals
9 :  13
Los Angeles Rams
Tampa Bay Buccaneers
Tampa Bay Buccaneers Latest matches
W L W L L L
Victories

2/6 (33%)

Draw

0/6 (0%)

Defeats

4/6 (67%)

Nov 23, 2025 - NFL

Tampa Bay Buccaneers
7 :  34
Los Angeles Rams

Nov 16, 2025 - NFL

Tampa Bay Buccaneers
32 :  44
Buffalo Bills

Nov 9, 2025 - NFL

New England Patriots
28 :  23
Tampa Bay Buccaneers

Oct 26, 2025 - NFL

Tampa Bay Buccaneers
23 :  3
New Orleans Saints

Oct 20, 2025 - NFL

Tampa Bay Buccaneers
9 :  24
Detroit Lions

Oct 12, 2025 - NFL

San Francisco 49ers
19 :  30
Tampa Bay Buccaneers
W L W L W L
Victories

3/6 (50%)

Draw

0/6 (0%)

Defeats

3/6 (50%)

Nov 9, 2025 - NFL

New England Patriots
28 :  23
Tampa Bay Buccaneers

Oct 12, 2025 - NFL

San Francisco 49ers
19 :  30
Tampa Bay Buccaneers

Sep 28, 2025 - NFL

Philadelphia Eagles
31 :  25
Tampa Bay Buccaneers

Sep 21, 2025 - NFL

New York Jets
27 :  29
Tampa Bay Buccaneers

Jan 12, 2025 - NFL

Washington Commanders
23 :  20
Tampa Bay Buccaneers

Jan 5, 2025 - NFL

New Orleans Saints
19 :  27
Tampa Bay Buccaneers
W W L W L L
Victories

3/6 (50%)

Draw

0/6 (0%)

Defeats

3/6 (50%)

Nov 23, 2025 - NFL

Tampa Bay Buccaneers
7 :  34
Los Angeles Rams

Nov 16, 2025 - NFL

Tampa Bay Buccaneers
32 :  44
Buffalo Bills

Oct 26, 2025 - NFL

Tampa Bay Buccaneers
23 :  3
New Orleans Saints

Oct 20, 2025 - NFL

Tampa Bay Buccaneers
9 :  24
Detroit Lions

Oct 5, 2025 - NFL

Tampa Bay Buccaneers
38 :  35
Seattle Seahawks

Sep 15, 2025 - NFL

Tampa Bay Buccaneers
20 :  19
Houston Texans

Arizona Cardinals - Tampa Bay Buccaneers Key Points

  1. The all-time series between Arizona and Tampa Bay is tied at 11 wins apiece.
  2. Tampa Bay won the last meeting on Christmas Day in 2022, 19-16 in OT, but the Cardinals have won three of the last five games.
  3. The Cardinals are 1-8 SU and 3-6 ATS in their last nine games.
  4. Betting Public: 86% of moneyline tickets and 90% of the handle are on the Buccaneers.
Up to $500+ to bet on Arizona Cardinals - Tampa Bay Buccaneers! 

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Our Arizona Cardinals vs Tampa Bay Buccaneers Prediction

Tampa Bay is the better overall team between the two, but I’m a bit concerned about whether Mayfield will be physical enough to make the plays the Bucs will need to in order to win this game. He's the kind of warrior who will want to play no matter what, and after what we saw last week from Teddy Bridgewater, they'll let him go if he says he can play. Brissett is going to throw for some serious yards on the Bucs' leaky pass defense. So, can we trust the Bucs to win? I think so, but I am not confident they’ll cover.

Our Arizona vs. Tampa Bay Pick: Buccaneers ML

Prediction:

 

Buccaneers ML

-197
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Arizona Cardinals vs Tampa Bay Buccaneers Picks